UniProt P04911
Histone H2A.1 (P04911)
Histone H2A.1 (UniProt P04911): 21 experimental structures and 1 predicted model on GenesisL1, 47 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04911
- Protein
- Histone H2A.1
- Experimental structures
- 21
- Predicted models
- 1
- Pockets
- 47 · 9 records with a druggable one
Structures
22 records of P04911 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ID3 | Crystal structure of the yeast nucleosome core particle reveals fundamental differences in… | x-ray diffraction | C, G | — | — |
| 1ID3 | Crystal structure of the yeast nucleosome core particle reveals fundamental differences in… | x-ray diffraction | C, G | — | — |
| 3T7K | Complex structure of Rtt107p and phosphorylated histone H2A | x-ray diffraction | C, D | — | — |
| 3T7K | Complex structure of RTT107P and phosphorylated histone H2A | x-ray diffraction | C, D | — | — |
| 4WNN | SPT16-H2A-H2B fact histone complex | x-ray diffraction | A, C, E, G | — | — |
| 5BT1 | Histone chaperone HIF1 playing with histone H2A-H2B dimer | x-ray diffraction | C | — | — |
| 6GEJ | Chromatin remodeller-nucleosome complex at 3.6 A resolution. | electron microscopy | E, F | — | 1 (best 0.80) |
| 6GEJ | Chromatin remodeller-nucleosome complex at 3.6 a resolution. | electron microscopy | E, F | — | — |
| 6GEN | Chromatin remodeller-nucleosome complex at 4.5 A resolution. | electron microscopy | E, F | — | 2 (best 0.80) |
| 6GEN | Chromatin remodeller-nucleosome complex at 4.5 a resolution. | electron microscopy | E, F | — | — |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | g, i | — | — |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | g, i | — | — |
| 7K78 | antibody and nucleosome complex | electron microscopy | C, G | — | 14 (best 0.73) |
| 7K78 | Antibody and nucleosome complex | electron microscopy | C, G | — | — |
| 7K7G | nucleosome and Gal4 complex | electron microscopy | C, G | — | 11 (best 0.75) |
| 7K7G | Nucleosome and GAL4 complex | electron microscopy | C, G | — | — |
| 7SSA | Cryo-EM structure of pioneer factor Cbf1 bound to the nucleosome | electron microscopy | C, G | — | 13 (best 0.80) |
| 8OW0 | Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome | electron microscopy | g, c | — | 2 (best 0.77) |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | g, c | — | 1 (best 0.80) |
| 8QZ0 | SWR1-hexasome-dimer complex | electron microscopy | E | — | 2 (best 0.81) |
| 9FBW | SWR1 lacking Swc5 subunit in complex with hexasome | electron microscopy | E | — | 1 (best 0.82) |
| P04911 | AlphaFold monomer V2.0 prediction for histone H2A.1 (P04911) | predicted | A | — | — |
Experiment against prediction
- 4WNN chain G against the predicted model P04911: TM-score 0.97, RMSD 0.55 Å
- 4WNN chain C against the predicted model P04911: TM-score 0.97, RMSD 0.62 Å
- 7SSA chain C against the predicted model P04911: TM-score 0.96, RMSD 0.72 Å
- 7K78 chain G against the predicted model P04911: TM-score 0.96, RMSD 0.73 Å
- 7K78 chain G against the predicted model P04911: TM-score 0.96, RMSD 0.73 Å
- 7K78 chain C against the predicted model P04911: TM-score 0.96, RMSD 0.75 Å
- 7K78 chain C against the predicted model P04911: TM-score 0.96, RMSD 0.75 Å
- 7SSA chain G against the predicted model P04911: TM-score 0.96, RMSD 0.84 Å
- 5BT1 chain C against the predicted model P04911: TM-score 0.95, RMSD 0.83 Å
- 4WNN chain A against the predicted model P04911: TM-score 0.95, RMSD 0.85 Å
Elsewhere
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