UniProt P04843
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (P04843)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (UniProt P04843): 6 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 37 pockets. Binding sites, druggability and experiment…
- UniProt
- P04843
- Protein
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 37 · 5 records with a druggable one
Structures
7 records of P04843 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6S7O | Cryo-EM structure of human oligosaccharyltransferase complex OST-A | electron microscopy | E | NAG, BMA, MAN, EGY, KZB, MG | 9 (best 0.75) |
| 6S7O | Cryo-EM structure of human oligosaccharyltransferase complex ost-a | electron microscopy | E | NAG, BMA, MAN, EGY, KZB, MG | — |
| 6S7T | Cryo-EM structure of human oligosaccharyltransferase complex OST-B | electron microscopy | E | NAG, BMA, MAN, EGY, KZB, MG | 11 (best 0.74) |
| 6S7T | Cryo-EM structure of human oligosaccharyltransferase complex ost-B | electron microscopy | E | NAG, BMA, MAN, EGY, KZB, MG | — |
| 8B6L | Subtomogram average of the human Sec61-TRAP-OSTA-translocon | electron microscopy | O | — | 3 (best 0.75) |
| 8PN9 | Structure of human oligosaccharyltransferase OST-A complex bound to NGI-1 | electron microscopy | E | NAG, BMA, MAN | 11 (best 0.78) |
| P04843 | AlphaFold monomer V2.0 prediction for dolichyl- diphosphooligosaccharide--protein… | predicted | A | — | 3 (best 0.53) |
Ligands
- BMA · beta-D-mannopyranose · in 5 records
- MAN · alpha-D-mannopyranose · in 5 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 5 records
- EGY · (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium · in 4 records
- KZB · (2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S}, 9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13, 18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol · in 4 records
- MG · Magnesium ion · in 4 records
Experiment against prediction
- 6S7T chain E against the predicted model P04843: TM-score 0.97, RMSD 1.30 Å
- 6S7T chain E against the predicted model P04843: TM-score 0.97, RMSD 1.30 Å
- 8B6L chain O against the predicted model P04843: TM-score 0.87, RMSD 3.79 Å
- 6S7O chain E against the predicted model P04843: TM-score 0.87, RMSD 3.99 Å
- 6S7O chain E against the predicted model P04843: TM-score 0.87, RMSD 3.99 Å
- 8PN9 chain E against the predicted model P04843: TM-score 0.86, RMSD 3.97 Å
Elsewhere
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