UniProt P04786
DNA topoisomerase 1 (P04786)
DNA topoisomerase 1 (UniProt P04786): 2 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04786
- Protein
- DNA topoisomerase 1
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
3 records of P04786 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OIS | Yeast DNA topoisomerase I, N-terminal fragment | x-ray diffraction | A | — | — |
| 1OIS | Yeast DNA topoisomerase I, N-terminal fragment | x-ray diffraction | A | — | — |
| P04786 | AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (P04786) | predicted | A | — | 7 (best 0.81) |
Experiment against prediction
- 1OIS chain A against the predicted model P04786: TM-score 0.97, RMSD 0.97 Å
- 1OIS chain A against the predicted model P04786: TM-score 0.97, RMSD 0.97 Å
Elsewhere
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