UniProt P04177
Tyrosine 3-monooxygenase (P04177)
Tyrosine 3-monooxygenase (UniProt P04177): 6 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04177
- Protein
- Tyrosine 3-monooxygenase
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
7 records of P04177 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1TOH | Tyrosine hydroxylase catalytic and tetramerization domains from rat | x-ray diffraction | A | — | — |
| 1TOH | Tyrosine hydroxylase catalytic and tetramerization domains from rat | x-ray diffraction | A | — | — |
| 2MDA | The Solution Structure of the Regulatory Domain of Tyrosine Hydroxylase | solution nmr | A, B | — | — |
| 2MDA | The solution structure of the regulatory domain of tyrosine hydroxylase | solution nmr | A, B | — | — |
| 2TOH | Tyrosine hydroxylase catalytic and tetramerization domains from rat | x-ray diffraction | A | — | — |
| 2TOH | Tyrosine hydroxylase catalytic and tetramerization domains from rat | x-ray diffraction | A | — | — |
| P04177 | AlphaFold monomer V2.0 prediction for tyrosine 3-monooxygenase (P04177) | predicted | A | — | 6 (best 0.76) |
Experiment against prediction
- 1TOH chain A against the predicted model P04177: TM-score 0.99, RMSD 0.59 Å
- 1TOH chain A against the predicted model P04177: TM-score 0.99, RMSD 0.59 Å
- 2TOH chain A against the predicted model P04177: TM-score 0.99, RMSD 0.85 Å
- 2TOH chain A against the predicted model P04177: TM-score 0.99, RMSD 0.85 Å
- 2MDA chain A against the predicted model P04177: TM-score 0.69, RMSD 2.91 Å
- 2MDA chain A against the predicted model P04177: TM-score 0.69, RMSD 2.91 Å
Elsewhere
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