UniProt P04037
Cytochrome c oxidase subunit 4, mitochondrial (P04037)
Cytochrome c oxidase subunit 4, mitochondrial (UniProt P04037), EC 1.9.3.1: 21 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 40 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P04037
- Protein
- Cytochrome c oxidase subunit 4, mitochondrial
- EC
- 1.9.3.1
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 40 · 9 records with a druggable one
Structures
22 records of P04037 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HR8 | Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant Complexed with Cytochrome C Oxidase IV… | x-ray diffraction | O, P, Q, R | — | — |
| 1HR8 | Yeast mitochondrial processing peptidase beta-E73Q mutant complexed with cytochrome C oxidase IV… | x-ray diffraction | O, P, Q, R | — | — |
| 2ODX | Solution structure of Zn(II)Cox4 | solution nmr | A | — | — |
| 2ODX | Solution structure of ZN(II)COX4 | solution nmr | A | — | — |
| 6GIQ | Saccharomyces cerevisiae respiratory supercomplex III2IV | electron microscopy | d | — | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | d, p | ZN | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | d, p | ZN | — |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | d, q | ZN | 4 (best 0.83) |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | d, q | ZN | — |
| 6T15 | The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae | electron microscopy | d | ZN | — |
| 6YMX | CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | d | ZN | 2 (best 0.84) |
| 6YMX | CIII2/CIV respiratory supercomplex from saccharomyces cerevisiae | electron microscopy | d | ZN | — |
| 6YMY | Cytochrome c oxidase from Saccharomyces cerevisiae | electron microscopy | d | ZN | 7 (best 0.83) |
| 6YMY | Cytochrome C oxidase from saccharomyces cerevisiae | electron microscopy | d | ZN | — |
| 7Z10 | Monomeric respiratory complex IV isolated from S. cerevisiae | electron microscopy | d | PEF, ZN | 7 (best 0.82) |
| 7Z10 | Monomeric respiratory complex IV isolated from S. cerevisiae | electron microscopy | d | PEF, ZN | 7 (best 0.82) |
| 8DH6 | Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid… | electron microscopy | d | PEF, ZN | 7 (best 0.84) |
| 8DH6 | Cryo-EM structure of saccharomyces cerevisiae cytochrome C oxidase (complex IV) extracted in lipid… | electron microscopy | d | ZN | — |
| 8E7S | III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 | electron microscopy | T, t | — | 2 (best 0.86) |
| 8EC0 | III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant | electron microscopy | T | — | 2 (best 0.88) |
| 9ETZ | III2IV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | d | ZN | 2 (best 0.83) |
| P04037 | AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 4, mitochondrial (P04037) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6HU9 chain d against the predicted model P04037: TM-score 0.96, RMSD 0.91 Å
- 6HU9 chain d against the predicted model P04037: TM-score 0.96, RMSD 0.91 Å
- 6HU9 chain p against the predicted model P04037: TM-score 0.96, RMSD 0.91 Å
- 6HU9 chain p against the predicted model P04037: TM-score 0.96, RMSD 0.91 Å
- 6T0B chain d against the predicted model P04037: TM-score 0.96, RMSD 0.87 Å
- 6T0B chain d against the predicted model P04037: TM-score 0.96, RMSD 0.87 Å
- 7Z10 chain d against the predicted model P04037: TM-score 0.95, RMSD 0.95 Å
- 7Z10 chain d against the predicted model P04037: TM-score 0.95, RMSD 0.95 Å
- 8DH6 chain d against the predicted model P04037: TM-score 0.95, RMSD 1.03 Å
- 8DH6 chain d against the predicted model P04037: TM-score 0.95, RMSD 1.03 Å
Elsewhere
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