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UniProt P03893

NADH-ubiquinone oxidoreductase chain 2 (P03893)

NADH-ubiquinone oxidoreductase chain 2 (UniProt P03893), EC 1.6.5.3, 7.1.1.2: 15 experimental structures on GenesisL1, 3 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P03893
Protein
NADH-ubiquinone oxidoreductase chain 2
EC
1.6.5.3, 7.1.1.2
Experimental structures
15
Predicted models
0
Ligands
3
Pockets
21 · 6 records with a druggable one

Structures

15 records of P03893 in the MolNFT archive: 15 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6G2JMouse mitochondrial complex I in the active stateelectron microscopyN3PE, CDL3 (best 0.85)
6G2JMouse mitochondrial complex I in the active stateelectron microscopyN3PE, CDL—
6G72Mouse mitochondrial complex I in the deactive stateelectron microscopyN——
6ZR2Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 aelectron microscopyN3PE, CDL—
6ZTQCryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 aelectron microscopyN3PE, CDL—
7AK5Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 Aelectron microscopyN3PE, CDL—
7AK5Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 aelectron microscopyN3PE, CDL—
7AK6Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 aelectron microscopyNCDL—
7B93Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 aelectron microscopyN3PE, CDL—
8IAQRespiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under…electron microscopyNCDL, 3PE6 (best 0.84)
8IBDRespiratory complex CI:CIII2, type II, Wild type mouse under cold temperatureelectron microscopyN3PE, CDL2 (best 0.85)
8IC4Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under cold…electron microscopyN3PE, CDL5 (best 0.84)
8PW6C respirasome from murine liverelectron microscopyN13PE, PC1, CDL2 (best 0.85)
8RGRClosed Complex I from murine liverelectron microscopyN3PE, PC1, CDL3 (best 0.87)
P03893AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 2 (P03893)———

Ligands

  • CDL · Cardiolipin · in 13 records
  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 12 records
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 2 records

Elsewhere

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