UniProt P03007
DNA polymerase III epsilon (P03007)
DNA polymerase III epsilon (UniProt P03007), EC 2.7.7.7: 22 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P03007
- Protein
- DNA polymerase III epsilon
- EC
- 2.7.7.7
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 11 · 2 records with a druggable one
Structures
23 records of P03007 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J53 | Structure of the N-terminal Exonuclease Domain of the Epsilon Subunit of E.coli DNA Polymerase III… | x-ray diffraction | A | — | — |
| 1J53 | Structure of the N-terminal exonuclease domain of the epsilon subunit of E.COLI DNA polymerase III… | x-ray diffraction | A | — | — |
| 1J54 | Structure of the N-terminal exonuclease domain of the epsilon subunit of E.coli DNA polymerase III… | x-ray diffraction | A | — | — |
| 1J54 | Structure of the N-terminal exonuclease domain of the epsilon subunit of E.COLI DNA polymerase III… | x-ray diffraction | A | — | — |
| 2GUI | Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit of E. coli DNA… | x-ray diffraction | A | — | — |
| 2GUI | Structure and function of cyclized versions of the proofreading exonuclease subunit of E. COLI DNA… | x-ray diffraction | A | — | — |
| 2IDO | Structure of the E. coli Pol III epsilon-Hot proofreading complex | x-ray diffraction | A, C | — | — |
| 2IDO | Structure of the E. COLI pol III epsilon-hot proofreading complex | x-ray diffraction | A, C | — | — |
| 2XY8 | Paramagnetic-based NMR structure of the complex between the N- terminal epsilon domain and the… | solution nmr | A | — | — |
| 2XY8 | Paramagnetic-based NMR structure of the complex between the N- terminal epsilon domain and the… | solution nmr | A | — | — |
| 4GX8 | Crystal structure of a DNA polymerase III alpha-epsilon chimera | x-ray diffraction | A, B, C, D | — | — |
| 4GX8 | Crystal structure of a DNA polymerase III alpha-epsilon chimera | x-ray diffraction | A, B, C, D | — | — |
| 4GX9 | Crystal structure of a DNA polymerase III alpha-epsilon chimera | x-ray diffraction | A, B, C, D | — | — |
| 4GX9 | Crystal structure of a DNA polymerase III alpha-epsilon chimera | x-ray diffraction | A, B, C, D | — | — |
| 5FKU | cryo-EM structure of the E. coli replicative DNA polymerase complex in DNA free state (DNA… | electron microscopy | D | — | — |
| 5FKU | Cryo-EM structure of the E. COLI replicative DNA polymerase complex in DNA free state (DNA… | electron microscopy | D | — | — |
| 5FKV | cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase… | electron microscopy | D | — | — |
| 5FKV | Cryo-EM structure of the E. COLI replicative DNA polymerase complex bound to DNA (DNA polymerase… | electron microscopy | D | — | — |
| 5FKW | cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase… | electron microscopy | D | — | 4 (best 0.80) |
| 5FKW | Cryo-EM structure of the E. COLI replicative DNA polymerase complex bound to DNA (DNA polymerase… | electron microscopy | D | — | — |
| 5M1S | Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to… | electron microscopy | D | — | 7 (best 0.82) |
| 5M1S | Cryo-EM structure of the E. COLI replicative DNA polymerase-clamp- exonuclase-theta complex bound… | electron microscopy | D | — | — |
| P03007 | AlphaFold monomer V2.0 prediction for DNA polymerase III subunit epsilon (P03007) | predicted | A | — | — |
Experiment against prediction
- 1J53 chain A against the predicted model P03007: TM-score 0.99, RMSD 0.42 Å
- 1J53 chain A against the predicted model P03007: TM-score 0.99, RMSD 0.42 Å
- 1J54 chain A against the predicted model P03007: TM-score 0.99, RMSD 0.43 Å
- 1J54 chain A against the predicted model P03007: TM-score 0.99, RMSD 0.43 Å
- 2GUI chain A against the predicted model P03007: TM-score 0.99, RMSD 0.52 Å
- 2GUI chain A against the predicted model P03007: TM-score 0.99, RMSD 0.52 Å
- 2IDO chain A against the predicted model P03007: TM-score 0.99, RMSD 0.60 Å
- 2IDO chain A against the predicted model P03007: TM-score 0.99, RMSD 0.60 Å
- 2IDO chain C against the predicted model P03007: TM-score 0.97, RMSD 1.34 Å
- 2IDO chain C against the predicted model P03007: TM-score 0.97, RMSD 1.34 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.