UniProt P02749
Beta-2-glycoprotein 1 (P02749)
Beta-2-glycoprotein 1 (UniProt P02749): 21 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02749
- Protein
- Beta-2-glycoprotein 1
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 2 · 1 record with a druggable one
Structures
22 records of P02749 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G4F | NMR structure of the fifth domain of human BETA2-glycoprotein I | solution nmr | A | — | — |
| 1G4F | NMR structure of the fifth domain of human BETA2-glycoprotein I | solution nmr | A | — | — |
| 1G4G | NMR structure of the fifth domain of human BETA2-glycoprotein I | solution nmr | A | — | — |
| 1G4G | NMR structure of the fifth domain of human BETA2-glycoprotein I | solution nmr | A | — | — |
| 1QUB | Crystal structure of the glycosylated five-domain human BETA2-glycoprotein I purified from blood… | x-ray diffraction | A | — | — |
| 1QUB | Crystal structure of the glycosylated five-domain human BETA2- glycoprotein I purified from blood… | x-ray diffraction | A | — | — |
| 2KRI | Structure of a complex between domain V of beta2-glycoprotein I and the fourth ligand-binding… | solution nmr | A | — | — |
| 2KRI | Structure of a complex between domain V of BETA2-glycoprotein I and the fourth ligand-binding… | solution nmr | A | — | — |
| 3OP8 | Crystal structure of the domain V from beta2-glycoprotein I | x-ray diffraction | A, B | — | — |
| 3OP8 | Crystal structure of the domain V from BETA2-glycoprotein I | x-ray diffraction | A, B | — | — |
| 4JHS | Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1 | x-ray diffraction | A | — | — |
| 4JHS | Crystal structure of a C-terminal two domain fragment of human beta-2- glycoprotein 1 | x-ray diffraction | A | — | — |
| 6V06 | Crystal structure of beta-2 glycoprotein I purified from plasma (PB2GPI) | x-ray diffraction | A | NAG, SO4 | — |
| 6V08 | Crystal structure of human recombinant beta-2 glycoprotein I (HRB2GPI) | x-ray diffraction | A | NAG, SO4 | — |
| 6V09 | Crystal structure of human recombinant Beta-2 glycoprotein I short tag (ST-B2GPI) | x-ray diffraction | A | NAG, SO4 | — |
| 6V09 | Crystal structure of human recombinant beta-2 glycoprotein I short tag (st-B2GPI) | x-ray diffraction | A | NAG, SO4 | — |
| 6XSD | Patient-derived B2GPI | x-ray diffraction | A | NAG | — |
| 6XST | Recombinant beta-2-glycoprotein I with putative membrane insertion loop | x-ray diffraction | A | NAG | — |
| 7JIK | Human recombinant beta-2-glycoprotein 1 | x-ray diffraction | A | NAG | — |
| 7KG4 | Recombinant Beta-2-Glycoprotein I antibody recognition loop mutant | x-ray diffraction | A, B | NAG, FUC | 2 (best 0.54) |
| 7KG4 | Recombinant beta-2-glycoprotein I antibody recognition loop mutant | x-ray diffraction | A, B | NAG, FUC | — |
| P02749 | AlphaFold monomer V2.0 prediction for beta-2-glycoprotein 1 (P02749) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2KRI chain A against the predicted model P02749: TM-score 0.95, RMSD 0.74 Å
- 2KRI chain A against the predicted model P02749: TM-score 0.95, RMSD 0.74 Å
- 3OP8 chain B against the predicted model P02749: TM-score 0.94, RMSD 0.77 Å
- 3OP8 chain B against the predicted model P02749: TM-score 0.94, RMSD 0.77 Å
- 7KG4 chain A against the predicted model P02749: TM-score 0.94, RMSD 1.85 Å
- 7KG4 chain A against the predicted model P02749: TM-score 0.94, RMSD 1.85 Å
- 6V08 chain A against the predicted model P02749: TM-score 0.94, RMSD 1.77 Å
- 3OP8 chain A against the predicted model P02749: TM-score 0.94, RMSD 0.82 Å
- 3OP8 chain A against the predicted model P02749: TM-score 0.94, RMSD 0.82 Å
- 6XST chain A against the predicted model P02749: TM-score 0.94, RMSD 1.80 Å
Elsewhere
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