UniProt P02741
C-reactive protein (P02741)
C-reactive protein (UniProt P02741): 28 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 156 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02741
- Protein
- C-reactive protein
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 156 · 9 records with a druggable one
Structures
29 records of P02741 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B09 | Human C-reactive protein complexed with phosphocholine | x-ray diffraction | A, B, C, D, E | — | — |
| 1B09 | Human C-reactive protein complexed with phosphocholine | x-ray diffraction | A, B, C, D, E | — | — |
| 1GNH | Human C-reactive protein | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1GNH | Human C-reactive protein | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1LJ7 | Crystal structure of calcium-depleted human C-reactive protein from perfectly twinned data | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1LJ7 | Crystal structure of calcium-depleted human C-reactive protein from perfectly twinned data | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3L2Y | The structure of C-reactive protein bound to phosphoethanolamine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3L2Y | The structure of C-reactive protein bound to phosphoethanolamine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3PVN | Triclinic form of Human C-Reactive Protein in complex with Zinc | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3PVN | Triclinic form of human C-reactive protein in complex with zinc | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3PVO | Monoclinic form of Human C-Reactive Protein | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3PVO | Monoclinic form of human C-reactive protein | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 7PK9 | C-reactive protein decamer at pH 7.5 | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA | 20 (best 0.78) |
| 7PK9 | C-reactive protein decamer at pH 7.5 | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA | — |
| 7PKB | C-reactive protein pentamer at pH 7.5 | electron microscopy | E, D, C, B, A | CA | — |
| 7PKD | C-reactive protein decamer at pH 7.5 with phosphocholine ligand | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA, PC | 20 (best 0.82) |
| 7PKD | C-reactive protein decamer at pH 7.5 with phosphocholine ligand | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA, PC | — |
| 7PKE | C-reactive protein pentamer at pH 7.5 with phosphocholine ligand | electron microscopy | E, D, C, B, A | CA, PC | 10 (best 0.64) |
| 7PKE | C-reactive protein pentamer at pH 7.5 with phosphocholine ligand | electron microscopy | E, D, C, B, A | CA, PC | — |
| 7PKF | C-reactive protein decamer at pH 5 | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA | 20 (best 0.80) |
| 7PKF | C-reactive protein decamer at pH 5 | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA | — |
| 7PKG | C-reactive protein pentamer at pH 5 | electron microscopy | E, D, C, B, A | CA | 15 (best 0.57) |
| 7PKG | C-reactive protein pentamer at pH 5 | electron microscopy | E, D, C, B, A | CA | — |
| 7PKH | C-reactive protein decamer at pH 5 with phosphocholine ligand | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA, PC | 20 (best 0.81) |
| 7PKH | C-reactive protein decamer at pH 5 with phosphocholine ligand | electron microscopy | J, F, G, H, I, E, D, C, B, A | CA, PC | — |
| 7TBA | Pentraxin - ligand complex | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | XQY, CA | 20 (best 0.80) |
| 8WV4 | C-reactive protein, pentamer | electron microscopy | A, B, C, D, E | CA | 11 (best 0.60) |
| 8WV5 | C-reactive protein, decamer | electron microscopy | E, A, B, C, D, F, G, I, J, H | CA | 20 (best 0.83) |
| P02741 | AlphaFold monomer V2.0 prediction for C-reactive protein (P02741) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3PVO chain S against the predicted model P02741: TM-score 1.00, RMSD 0.23 Å
- 3PVO chain S against the predicted model P02741: TM-score 1.00, RMSD 0.23 Å
- 3PVO chain I against the predicted model P02741: TM-score 1.00, RMSD 0.24 Å
- 3PVO chain I against the predicted model P02741: TM-score 1.00, RMSD 0.24 Å
- 3PVO chain A against the predicted model P02741: TM-score 1.00, RMSD 0.24 Å
- 3PVO chain A against the predicted model P02741: TM-score 1.00, RMSD 0.24 Å
- 3PVN chain R against the predicted model P02741: TM-score 1.00, RMSD 0.24 Å
- 3PVN chain R against the predicted model P02741: TM-score 1.00, RMSD 0.24 Å
- 3PVO chain K against the predicted model P02741: TM-score 1.00, RMSD 0.25 Å
- 3PVO chain K against the predicted model P02741: TM-score 1.00, RMSD 0.25 Å
Elsewhere
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