UniProt P02340
Cellular tumor antigen P53 (P02340)
Cellular tumor antigen P53 (UniProt P02340): 16 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02340
- Protein
- Cellular tumor antigen P53
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
17 records of P02340 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HU8 | Crystal structure of the mouse P53 core DNA-binding domain at 2.7A resolution | x-ray diffraction | A, B, C | — | — |
| 1HU8 | Crystal structure of the mouse P53 core DNA-binding domain at 2.7A resolution | x-ray diffraction | A, B, C | — | — |
| 2GEQ | Crystal Structure of a p53 Core Dimer Bound to DNA | x-ray diffraction | A, B | — | — |
| 2GEQ | Crystal structure of a P53 core dimer bound to DNA | x-ray diffraction | A, B | — | — |
| 2IOI | Crystal structure of the mouse p53 core domain at 1.55 A | x-ray diffraction | A | — | — |
| 2IOI | Crystal structure of the mouse P53 core domain at 1.55 a | x-ray diffraction | A | — | — |
| 2IOM | Mouse p53 core domain soaked with 2-propanol | x-ray diffraction | A | — | — |
| 2IOM | Mouse P53 core domain soaked with 2-propanol | x-ray diffraction | A | — | — |
| 2IOO | Crystal structure of the mouse p53 core domain | x-ray diffraction | A | — | — |
| 2IOO | Crystal structure of the mouse P53 core domain | x-ray diffraction | A | — | — |
| 2P52 | mouse p53 DNA-binding domain in zinc-free oxidized state | x-ray diffraction | A | — | — |
| 2P52 | Mouse P53 DNA-binding domain in zinc-free oxidized state | x-ray diffraction | A | — | — |
| 3EXJ | Crystal Structure of a p53 Core Tetramer Bound to DNA | x-ray diffraction | A, B | — | — |
| 3EXJ | Crystal structure of a P53 core tetramer bound to DNA | x-ray diffraction | A, B | — | — |
| 3EXL | Crystal Structure of a p53 Core Tetramer Bound to DNA | x-ray diffraction | A | — | — |
| 3EXL | Crystal structure of a P53 core tetramer bound to DNA | x-ray diffraction | A | — | — |
| P02340 | AlphaFold monomer V2.0 prediction for cellular tumor antigen P53 (P02340) | predicted | A | — | 4 (best 0.39) |
Experiment against prediction
- 2IOI chain A against the predicted model P02340: TM-score 0.99, RMSD 0.51 Å
- 2IOI chain A against the predicted model P02340: TM-score 0.99, RMSD 0.51 Å
- 2IOO chain A against the predicted model P02340: TM-score 0.99, RMSD 0.52 Å
- 2IOO chain A against the predicted model P02340: TM-score 0.99, RMSD 0.52 Å
- 2IOM chain A against the predicted model P02340: TM-score 0.99, RMSD 0.54 Å
- 2IOM chain A against the predicted model P02340: TM-score 0.99, RMSD 0.54 Å
- 1HU8 chain A against the predicted model P02340: TM-score 0.99, RMSD 0.54 Å
- 1HU8 chain A against the predicted model P02340: TM-score 0.99, RMSD 0.54 Å
- 2GEQ chain B against the predicted model P02340: TM-score 0.99, RMSD 0.56 Å
- 2GEQ chain B against the predicted model P02340: TM-score 0.99, RMSD 0.56 Å
Elsewhere
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