UniProt P02259
Histone H5 (P02259)
Histone H5 (UniProt P02259): 10 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02259
- Protein
- Histone H5
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
11 records of P02259 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HST | Crystal structure of globular domain of histone H5 and its implications for nucleosome binding | x-ray diffraction | A, B | — | — |
| 1HST | Crystal structure of globular domain of histone H5 and its implications for nucleosome binding | x-ray diffraction | A, B | — | — |
| 4QLC | Crystal structure of chromatosome at 3.5 angstrom resolution | x-ray diffraction | U | — | — |
| 4QLC | Crystal structure of chromatosome at 3.5 ångström resolution | x-ray diffraction | U | — | — |
| 5WCU | Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5 | x-ray diffraction | U, V | — | — |
| 5WCU | Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5 | x-ray diffraction | U, V | — | — |
| 7C0J | Crystal structure of chimeric mutant of GH5 in complex with Z-DNA | x-ray diffraction | A, B | — | 1 (best 0.46) |
| 7C0J | Crystal structure of chimeric mutant of GH5 in complex with Z-DNA | x-ray diffraction | A, B | — | — |
| 7XVM | Crystal Structure of Nucleosome-H5 Linker Histone Assembly (sticky-169a DNA fragment) | x-ray diffraction | U, V | — | — |
| 8XJV | Structural basis for the linker histone H5-nucleosome binding and chromatin compaction | electron microscopy | Ah, Ai, Aj, Ak, Al, Am, An, Ao, Ap, Aq, Ar, As | — | 1 (best 0.85) |
| P02259 | AlphaFold monomer V2.0 prediction for histone H5 (P02259) | predicted | A | — | — |
Experiment against prediction
- 4QLC chain U against the predicted model P02259: TM-score 0.95, RMSD 1.16 Å
- 4QLC chain U against the predicted model P02259: TM-score 0.95, RMSD 1.16 Å
- 5WCU chain V against the predicted model P02259: TM-score 0.93, RMSD 1.25 Å
- 5WCU chain U against the predicted model P02259: TM-score 0.93, RMSD 1.28 Å
- 5WCU chain U against the predicted model P02259: TM-score 0.93, RMSD 1.28 Å
- 1HST chain A against the predicted model P02259: TM-score 0.90, RMSD 1.14 Å
- 1HST chain A against the predicted model P02259: TM-score 0.90, RMSD 1.14 Å
- 7XVM chain V against the predicted model P02259: TM-score 0.89, RMSD 1.53 Å
- 7C0J chain B against the predicted model P02259: TM-score 0.88, RMSD 1.34 Å
- 7C0J chain B against the predicted model P02259: TM-score 0.88, RMSD 1.34 Å
Elsewhere
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