UniProt P01921
H-2 class II histocompatibility antigen, A-D beta chain (P01921)
H-2 class II histocompatibility antigen, A-D beta chain (UniProt P01921): 4 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01921
- Protein
- H-2 class II histocompatibility antigen, A-D beta chain
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 7 · 0 records with a druggable one
Structures
5 records of P01921 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IAD | Class II MHC I-ad in complex with an influenza hemagglutinin peptide 126-138 | x-ray diffraction | B | — | 3 (best 0.37) |
| 2IAD | Class II MHC I-ad in complex with an influenza hemagglutinin peptide 126-138 | x-ray diffraction | B | — | — |
| 7RDV | TFH TCR bound to MHC Class II IAd presenting aggrecan epitope | x-ray diffraction | B | — | 4 (best 0.50) |
| 7RDV | Tfh TCR bound to MHC class II iad presenting aggrecan epitope | x-ray diffraction | B | — | — |
| P01921 | AlphaFold monomer V2.0 prediction for H-2 class II histocompatibility antigen, a-D beta chain… | predicted | A | — | — |
Experiment against prediction
- 7RDV chain B against the predicted model P01921: TM-score 0.86, RMSD 2.23 Å
- 7RDV chain B against the predicted model P01921: TM-score 0.86, RMSD 2.23 Å
- 2IAD chain B against the predicted model P01921: TM-score 0.78, RMSD 2.71 Å
- 2IAD chain B against the predicted model P01921: TM-score 0.78, RMSD 2.71 Å
Elsewhere
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