UniProt P01876
Immunoglobulin alpha-1 heavy constant (P01876)
Immunoglobulin alpha-1 heavy constant (UniProt P01876): 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01876
- Protein
- Immunoglobulin alpha-1 heavy constant
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
16 records of P01876 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IGA | Model of human IGA1 determined by solution scattering curve-fitting and homology modelling | solution scattering | A, B | — | — |
| 1IGA | Model of human IGA1 determined by solution scattering curve- fitting and homology modelling | solution scattering | A, B | — | — |
| 1OW0 | Crystal structure of human FcaRI bound to IgA1-Fc | x-ray diffraction | A, B | — | — |
| 1OW0 | Crystal structure of human fcari bound to IGA1-Fc | x-ray diffraction | A, B | — | — |
| 2QEJ | Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1 | x-ray diffraction | A, B | — | — |
| 2QEJ | Crystal structure of a staphylococcus aureus protein (SSL7) in complex with Fc of human IGA1 | x-ray diffraction | A, B | — | — |
| 2QTJ | Solution structure of human dimeric immunoglobulin A | solution scattering | A, B, C, D | — | — |
| 2QTJ | Solution structure of human dimeric immunoglobulin a | solution scattering | A, B, C, D | — | — |
| 3CHN | Solution structure of human secretory IgA1 | solution scattering | A, B, D, C | — | — |
| 3CHN | Solution structure of human secretory IGA1 | solution scattering | A, B, D, C | — | — |
| 6LX3 | Cryo-EM structure of human secretory immunoglobulin a | electron microscopy | A, B, C, D | — | — |
| 6LXW | Cryo-EM structure of human secretory immunoglobulin a in complex with the N-terminal domain of spsa | electron microscopy | A, B, C, D | — | — |
| 6UE7 | Structure of dimeric siga complex | electron microscopy | A, B, F, G | NAG | — |
| 6XJA | Streptococcus pneumoniae IGA1 protease with IGA1 substrate | electron microscopy | A, B | — | — |
| 7UVL | IgA1 Protease with IgA1 substrate | electron microscopy | B, A | — | 4 (best 0.61) |
| P01876 | AlphaFold monomer V2.0 prediction for immunoglobulin heavy constant alpha 1 (P01876) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 7UVL chain A against the predicted model P01876: TM-score 0.95, RMSD 1.22 Å
- 1OW0 chain A against the predicted model P01876: TM-score 0.95, RMSD 1.30 Å
- 1OW0 chain A against the predicted model P01876: TM-score 0.95, RMSD 1.30 Å
- 7UVL chain B against the predicted model P01876: TM-score 0.95, RMSD 1.29 Å
- 2QEJ chain A against the predicted model P01876: TM-score 0.94, RMSD 1.37 Å
- 2QEJ chain A against the predicted model P01876: TM-score 0.94, RMSD 1.37 Å
- 2QEJ chain B against the predicted model P01876: TM-score 0.93, RMSD 1.52 Å
- 2QEJ chain B against the predicted model P01876: TM-score 0.93, RMSD 1.52 Å
- 6LX3 chain B against the predicted model P01876: TM-score 0.93, RMSD 1.60 Å
- 6LX3 chain C against the predicted model P01876: TM-score 0.92, RMSD 1.38 Å
Elsewhere
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