UniProt P01871
Immunoglobulin heavy constant mu (P01871)
Immunoglobulin heavy constant mu (UniProt P01871): 19 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 218 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01871
- Protein
- Immunoglobulin heavy constant mu
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 218 · 14 records with a druggable one
Structures
20 records of P01871 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2AGJ | Crystal Structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural… | x-ray diffraction | H | — | — |
| 2AGJ | Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural… | x-ray diffraction | H | — | — |
| 6KXS | Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 17 (best 0.89) |
| 6KXS | Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pigr | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | — |
| 7K0C | Structure of Secretory IgM Core | electron microscopy | A, B, K, L, I, J, E, H, G, F | — | 18 (best 0.88) |
| 7K0C | Structure of secretory IgM core | electron microscopy | A, B, K, L, I, J, E, H, G, F | — | — |
| 7WSP | Structure of a membrane protein M | electron microscopy | B, D | — | 13 (best 0.80) |
| 7XQ8 | Structure of human B-cell antigen receptor of the IgM isotype | electron microscopy | — | — | |
| 7Y09 | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 19 (best 0.87) |
| 7Y0H | Cryo-EM structure of human IgM-Fc in complex with the J chain and the P. falciparum VAR2CSA FCR3 | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 14 (best 0.86) |
| 7Y0J | Cryo-EM structure of human IgM-Fc in complex with the J chain and the P. falciparum TM284VAR1 | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 18 (best 0.83) |
| 7YG2 | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP2 | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 20 (best 0.87) |
| 7YSG | Cryo-EM structure of human FcmR bound to sIgM | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | — |
| 7YTC | Cryo-EM structure of human FcmR bound to IgM-Fc/J | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 20 (best 0.87) |
| 7YTD | Cryo-EM structure of four human FcmR bound to IgM-Fc/J | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 17 (best 0.85) |
| 8GZN | IgM-var2CSA complex | electron microscopy | A, B, C, D, E, F, G, H, K, L | — | 8 (best 0.84) |
| 8WYR | Cryo-EM structure of human CD5L bound to IgM-Fc/J | electron microscopy | A, B, C, D, E, F, G, H, K, L | NAG | 20 (best 0.86) |
| 8WYS | Local map of human CD5L bound to IgM-Fc/J | electron microscopy | A, L | NAG | 10 (best 0.66) |
| 9ARV | CryoEM structure of AMETA-A3 | electron microscopy | A, B, C, D, E, L, M, N, O, P | NAG | 20 (best 0.83) |
| P01871 | AlphaFold monomer V2.0 prediction for immunoglobulin heavy constant mu (P01871) | predicted | A | — | 4 (best 0.56) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 12 records
Experiment against prediction
- 7Y0J chain G against the predicted model P01871: TM-score 0.91, RMSD 1.41 Å
- 7Y09 chain D against the predicted model P01871: TM-score 0.91, RMSD 1.38 Å
- 7YTD chain E against the predicted model P01871: TM-score 0.90, RMSD 1.49 Å
- 8GZN chain D against the predicted model P01871: TM-score 0.90, RMSD 1.55 Å
- 8GZN chain F against the predicted model P01871: TM-score 0.90, RMSD 1.64 Å
- 7Y0J chain D against the predicted model P01871: TM-score 0.89, RMSD 1.61 Å
- 7YTC chain D against the predicted model P01871: TM-score 0.89, RMSD 1.62 Å
- 7K0C chain L against the predicted model P01871: TM-score 0.89, RMSD 1.63 Å
- 7K0C chain L against the predicted model P01871: TM-score 0.89, RMSD 1.63 Å
- 7YTD chain H against the predicted model P01871: TM-score 0.89, RMSD 1.62 Å
Elsewhere
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