UniProt P01859
Ig gamma-2 chain C region (P01859)
Ig gamma-2 chain C region (UniProt P01859): 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01859
- Protein
- Ig gamma-2 chain C region
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 10 · 0 records with a druggable one
Structures
9 records of P01859 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HAF | Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form) | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | 1 (best 0.29) |
| 4HAF | Crystal structure of Fc-fragment of human IGG2 antibody (primitive crystal form) | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | 1 (best 0.29) |
| 4HAG | Crystal structure of fc-fragment of human IgG2 antibody (centered crystal form) | x-ray diffraction | A | NAG, BMA, MAN | — |
| 4HAG | Crystal structure of Fc-fragment of human IGG2 antibody (centered crystal form) | x-ray diffraction | A | NAG, BMA, MAN | — |
| 4L4J | Crystal structure of fc-fragment of human IgG2-Sigma antibody | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | 3 (best 0.48) |
| 4L4J | Crystal structure of Fc-fragment of human IGG2-sigma antibody | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | 3 (best 0.48) |
| 7LUS | IgG2 Fc Charge Pair Mutation version 1 (CPMv1) | x-ray diffraction | B, A | NAG, BMA, MAN, FUC | 2 (best 0.35) |
| 7LUS | IGG2 Fc charge pair mutation version 1 (CPMV1) | x-ray diffraction | B, A | NAG, BMA, MAN, FUC | — |
| P01859 | AlphaFold monomer V2.0 prediction for immunoglobulin heavy constant gamma 2 (P01859) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7LUS chain B against the predicted model P01859: TM-score 0.98, RMSD 0.81 Å
- 7LUS chain B against the predicted model P01859: TM-score 0.98, RMSD 0.81 Å
- 4HAF chain B against the predicted model P01859: TM-score 0.98, RMSD 0.82 Å
- 4HAF chain B against the predicted model P01859: TM-score 0.98, RMSD 0.82 Å
- 4HAG chain A against the predicted model P01859: TM-score 0.96, RMSD 1.16 Å
- 4HAG chain A against the predicted model P01859: TM-score 0.96, RMSD 1.16 Å
- 7LUS chain A against the predicted model P01859: TM-score 0.94, RMSD 1.34 Å
- 7LUS chain A against the predicted model P01859: TM-score 0.94, RMSD 1.34 Å
- 4L4J chain A against the predicted model P01859: TM-score 0.94, RMSD 1.61 Å
- 4L4J chain A against the predicted model P01859: TM-score 0.94, RMSD 1.61 Å
Elsewhere
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