UniProt P01579
Interferon gamma (P01579)
Interferon gamma (UniProt P01579): 14 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01579
- Protein
- Interferon gamma
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
15 records of P01579 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EKU | Crystal structure of a biologically active single chain mutant of human ifn-gamma | x-ray diffraction | A, B | — | — |
| 1EKU | Crystal structure of a biologically active single chain mutant of human ifn-gamma | x-ray diffraction | A, B | — | — |
| 1FG9 | 3:1 complex of interferon-gamma receptor with interferon-gamma dimer | x-ray diffraction | A, B | — | — |
| 1FG9 | 3:1 complex of interferon-gamma receptor with interferon- gamma dimer | x-ray diffraction | A, B | — | — |
| 1FYH | 1:1 complex between an interferon gamma single-chain variant and its receptor | x-ray diffraction | A, D | — | — |
| 1FYH | 1:1 complex between an interferon gamma single-chain variant and its receptor | x-ray diffraction | A, D | — | — |
| 1HIG | Three-dimensional structure of recombinant human interferon-gamma. | x-ray diffraction | A, B, C, D | — | — |
| 1HIG | Three-dimensional structure of recombinant human interferon- gamma. | x-ray diffraction | A, B, C, D | — | — |
| 3BES | Structure of a Poxvirus ifngbp/ifng Complex | x-ray diffraction | L | — | — |
| 3BES | Structure of a poxvirus IFNGBP/IFNG complex | x-ray diffraction | L | — | — |
| 6E3K | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | A, B | NAG | 5 (best 0.78) |
| 6E3K | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | A, B | NAG | — |
| 6E3L | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | A, B | NAG | 5 (best 0.76) |
| 6E3L | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | A, B | NAG | — |
| P01579 | AlphaFold monomer V2.0 prediction for interferon gamma (P01579) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
Experiment against prediction
- 6E3K chain A against the predicted model P01579: TM-score 0.98, RMSD 0.66 Å
- 6E3K chain A against the predicted model P01579: TM-score 0.98, RMSD 0.66 Å
- 6E3L chain A against the predicted model P01579: TM-score 0.98, RMSD 0.66 Å
- 6E3L chain A against the predicted model P01579: TM-score 0.98, RMSD 0.66 Å
- 6E3K chain B against the predicted model P01579: TM-score 0.98, RMSD 0.73 Å
- 6E3K chain B against the predicted model P01579: TM-score 0.98, RMSD 0.73 Å
- 6E3L chain B against the predicted model P01579: TM-score 0.98, RMSD 0.76 Å
- 6E3L chain B against the predicted model P01579: TM-score 0.98, RMSD 0.76 Å
- 3BES chain L against the predicted model P01579: TM-score 0.97, RMSD 1.00 Å
- 3BES chain L against the predicted model P01579: TM-score 0.97, RMSD 1.00 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.