UniProt P01034
Cystatin-C (P01034)
Cystatin-C (UniProt P01034): 22 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01034
- Protein
- Cystatin-C
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
23 records of P01034 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G96 | Human cystatin C; dimeric form with 3D domain swapping | x-ray diffraction | A | — | — |
| 1G96 | Human cystatin C; dimeric form with 3D domain swapping | x-ray diffraction | A | — | — |
| 1R4C | N-Truncated Human Cystatin C; Dimeric Form With 3D Domain Swapping | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1R4C | N-truncated human cystatin C; dimeric form with 3D domain swapping | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1TIJ | 3D Domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets | x-ray diffraction | A, B | — | — |
| 1TIJ | 3D domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets | x-ray diffraction | A, B | — | — |
| 3GAX | Crystal structure of monomeric human cystatin C stabilized against aggregation | x-ray diffraction | A, B | — | — |
| 3GAX | Crystal structure of monomeric human cystatin C stabilized against aggregation | x-ray diffraction | A, B | — | — |
| 3NX0 | Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin… | x-ray diffraction | A, B | — | — |
| 3NX0 | Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin… | x-ray diffraction | A, B | — | — |
| 3PS8 | Crystal structure of L68V mutant of human cystatin C | x-ray diffraction | A | — | — |
| 3PS8 | Crystal structure of L68V mutant of human cystatin C | x-ray diffraction | A | — | — |
| 3QRD | Crystal structure of L68V mutant of human cystatin C | x-ray diffraction | A, B, C, D | — | — |
| 3QRD | Crystal structure of L68V mutant of human cystatin C | x-ray diffraction | A, B, C, D | — | — |
| 3S67 | Crystal structure of V57P mutant of human cystatin C | x-ray diffraction | A | — | — |
| 3S67 | Crystal structure of V57P mutant of human cystatin C | x-ray diffraction | A | — | — |
| 3SVA | Crystal structure of V57D mutant of human cystatin C | x-ray diffraction | A | — | — |
| 3SVA | Crystal structure of V57D mutant of human cystatin C | x-ray diffraction | A | — | — |
| 6ROA | Crystal structure of V57G mutant of human cystatin C | x-ray diffraction | A, B | — | 3 (best 0.61) |
| 6ROA | Crystal structure of V57G mutant of human cystatin C | x-ray diffraction | A, B | — | — |
| 6RPV | Extremely stable monomeric variant of human cystatin C with single amino acid substitution | solution nmr, solution scattering | A | — | 2 (best 0.47) |
| 6RPV | Extremely stable monomeric variant of human cystatin C with single amino acid substitution | solution nmr; solution scattering | A | — | 2 (best 0.47) |
| P01034 | AlphaFold monomer V2.0 prediction for cystatin-C (P01034) | predicted | A | — | — |
Experiment against prediction
- 3GAX chain A against the predicted model P01034: TM-score 0.96, RMSD 0.87 Å
- 3GAX chain A against the predicted model P01034: TM-score 0.96, RMSD 0.87 Å
- 3GAX chain B against the predicted model P01034: TM-score 0.96, RMSD 0.88 Å
- 3GAX chain B against the predicted model P01034: TM-score 0.96, RMSD 0.88 Å
- 3NX0 chain A against the predicted model P01034: TM-score 0.96, RMSD 0.92 Å
- 3NX0 chain A against the predicted model P01034: TM-score 0.96, RMSD 0.92 Å
- 6ROA chain A against the predicted model P01034: TM-score 0.95, RMSD 0.98 Å
- 6ROA chain A against the predicted model P01034: TM-score 0.95, RMSD 0.98 Å
- 3NX0 chain B against the predicted model P01034: TM-score 0.94, RMSD 1.07 Å
- 3NX0 chain B against the predicted model P01034: TM-score 0.94, RMSD 1.07 Å
Elsewhere
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