UniProt P00953
Tryptophan--tRNA ligase (P00953)
Tryptophan--tRNA ligase (UniProt P00953), EC 6.1.1.2: 29 experimental structures on GenesisL1, 7 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P00953
- Protein
- Tryptophan--tRNA ligase
- EC
- 6.1.1.2
- Experimental structures
- 29
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 1 · 1 record with a druggable one
Structures
29 records of P00953 in the MolNFT archive: 29 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D2R | 2.9 a crystal structure of ligand-free tryptophanyl-tRNA synthetase: domain movements fragment the… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1D2R | 2.9 a crystal structure of ligand-free tryptophanyl-tRNA synthetase: domain movements fragment the… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1I6K | 1.7 high resolution experimental phases for tryptophanyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 1I6K | 1.7 high resolution experimental phases for tryptophanyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 1I6L | 1.7 high resolution experimental phases for tryptophanyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 1I6L | 1.7 high resolution experimental phases for tryptophanyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 1I6M | 1.7 high resolution experimental phases for tryptophanyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 1I6M | 1.7 high resolution experimental phases for tryptophanyl-tRNA synthetase complexed with… | x-ray diffraction | A | — | — |
| 1M83 | Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with ATP in a Closed, Pre-transition… | x-ray diffraction | A | — | — |
| 1M83 | Crystal structure of tryptophanyl-tRNA synthetase complexed with ATP in a closed, pre-transition… | x-ray diffraction | A | — | — |
| 1MAU | Crystal structure of Tryptophanyl-tRNA Synthetase Complexed with ATP and Tryptophanamide in a… | x-ray diffraction | A | — | — |
| 1MAU | Crystal structure of tryptophanyl-tRNA synthetase complexed with ATP and tryptophanamide in a… | x-ray diffraction | A | — | — |
| 1MAW | Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with ATP in an Open Conformation | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1MAW | Crystal structure of tryptophanyl-tRNA synthetase complexed with ATP in an open conformation | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1MB2 | Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1MB2 | Crystal structure of tryptophanyl-tRNA synthetase complexed with tryptophan in an open conformation | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2OV4 | Crystal structure of B. stearothermophilus tryptophanyl tRNA synthetase in complex with adenosine… | x-ray diffraction | A | — | — |
| 2OV4 | Crystal structure of B. stearothermophilus tryptophanyl tRNA synthetase in complex with adenosine… | x-ray diffraction | A | — | — |
| 3FHJ | Independent saturation of three TrpRS subsites generates a partially-assembled state similar to… | x-ray diffraction | A, D, B, C, E, F | — | — |
| 3FHJ | Independent saturation of three trprs subsites generates a partially- assembled state similar to… | x-ray diffraction | A, D, B, C, E, F | — | — |
| 3FI0 | Crystal Structure Analysis of B. stearothermophilus Tryptophanyl-tRNA Synthetase Complexed with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | — | — |
| 3FI0 | Crystal structure analysis of B. stearothermophilus tryptophanyl-tRNA synthetase complexed with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | — | — |
| 5DK4 | Crystal structure analysis of Tryptophanyl-trna synthetase from Bacillus stearothermophilus in… | x-ray diffraction | A | ATP, MG, 5BX | — |
| 5DK4 | Crystal structure analysis of tryptophanyl-tRNA synthetase from bacillus stearothermophilus in… | x-ray diffraction | A | — | — |
| 7CKI | Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with… | x-ray diffraction | A | 9E0, MG, K, ATP | 1 (best 0.77) |
| 7CKI | Crystal structure of tryptophanyl-tRNA synthetase from bacillus stearothermophilus in complex with… | x-ray diffraction | A | 9E0, MG, K, ATP | — |
| 7CMS | Crystal structure of tryptophanyl-tRNA synthetase from bacillus stearothermophilus in complex with… | x-ray diffraction | A, B | 9E0, PO4 | — |
| 7EER | Crystal structure of tryptophanyl-tRNA synthetase from bacillus stearothermophilus in complex with… | x-ray diffraction | A, B, C, D | ATP, ZCW | — |
| P00953 | AlphaFold monomer V2.0 prediction for tryptophan--tRNA ligase (P00953) | — | — | — |
Ligands
- ATP · Adenosine-5'-triphosphate · in 4 records
- 9E0 · (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4, 12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid · in 3 records
- MG · Magnesium ion · in 3 records
- K · Potassium ion · in 2 records
- 5BX · (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one · in 1 record
- PO4 · Phosphate ion · in 1 record
- ZCW · 2-(1H-indol-3-yl)ethanol · in 1 record
Elsewhere
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