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Ligand · ZCW

ZCW · 2-(1H-indol-3-yl)ethanol

ZCW, 2-(1H-indol-3-yl)ethanol (C10 H11 N O, 161.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
ZCW
Formula
C10 H11 N O
Class
ligand
Structures
8
PDB entries
6

Binding sites

ZCW in 8 structures; the first of them:

  • 6E35 · Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and… · ZCW A504 · binds VAL170, ALA174, LEU207, PHE270, PHE273, LEU339, LEU342, ARG343 and 1 more
  • 6K80 · Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Complex with… · ZCW A301 · binds HIS184, ARG200, MET201, GLN202, VAL221, GLY222, ILE223, GLN224
  • 5WMV · Structural insights into substrate and inhibitor binding sites in human indoleamine… · ZCW A503 · binds ALA174, LEU207, PHE270, PHE273, LEU339, LEU342, ARG343, HIS346
  • 5WMX · Structural insights into substrate and inhibitor binding sites in human indoleamine… · ZCW A503 · binds VAL170, LEU207, GLY270, PHE273, LEU339, LEU342, ARG343, HIS346
  • 6CXV · Structure of the S167H mutant of human indoleamine 2,3 dioxygenase in complex with… · ZCW A504 · binds VAL170, PHE270, LEU339, LEU342, ARG343, HIS346
  • 6E35 · Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-TRP and… · ZCW A504 · binds ALA174, LEU207, PHE270, PHE273, LEU339, LEU342, ARG343, HIS346
  • 6K80 · Crystal structure of drosophila melanogaster dopamine N- acetyltransferase in complex… · ZCW A301 · binds HIS184, ARG200, MET201, GLN202, VAL221, GLY222, ILE223, GLN224
  • 7EER · Crystal structure of tryptophanyl-tRNA synthetase from bacillus stearothermophilus in… · ZCW A402 · binds PHE5, SER6, GLY7, VAL40, HIS43, TYR125, MET129, ASP132 and 4 more

Residues it binds most

LEU 10, PHE 14, VAL 13, HIS 14, ARG 10, ILE 8, GLN 6, GLY 8, MET 8, SER 8 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • CYN · Cyanide ion
  • ACO · Acetyl coenzyme *A
  • ATP · Adenosine-5'-triphosphate
  • TRP · Tryptophan

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