UniProt P00738
Haptoglobin (P00738)
Haptoglobin (UniProt P00738): 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00738
- Protein
- Haptoglobin
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 39 · 5 records with a druggable one
Structures
12 records of P00738 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4WJG | Structure of T. brucei haptoglobin-hemoglobin receptor binding to human haptoglobin-hemoglobin | x-ray diffraction | C, H, M, R, W, 2 | NAG | 14 (best 0.83) |
| 4WJG | Structure of T. brucei haptoglobin-hemoglobin receptor binding to human haptoglobin-hemoglobin | x-ray diffraction | C, H, M, R, W, 2 | — | — |
| 4X0L | Human haptoglobin-haemoglobin complex | x-ray diffraction | C | — | — |
| 4X0L | Human haptoglobin-haemoglobin complex | x-ray diffraction | C | — | — |
| 5HU6 | Structure of the T. brucei haptoglobin-haemoglobin receptor bound to human haptolgobin-haemoglobin | x-ray diffraction | C | NAG | — |
| 5HU6 | Structure of the T. brucei haptoglobin-haemoglobin receptor bound to human haptolgobin-haemoglobin | x-ray diffraction | C | — | — |
| 6TB2 | Structure of human haptoglobin-hemoglobin bound to S. aureus isdh | x-ray diffraction | C | — | — |
| 8XMP | Structure of CD163 in complex with Hb-Hp | electron microscopy | 2 | NAG, CA | 5 (best 0.65) |
| 8XMW | Local refinement of Hb-Hp bind to CD163 | electron microscopy | 2 | NAG, CA | 9 (best 0.68) |
| 9FHB | Cryo-EM structure of human CD163 SRCR2-4 in complex with haptoglobin-hemoglobin | electron microscopy | C | NAG | 7 (best 0.79) |
| 9FMU | Cryo-EM structure of human CD163 SRCR1-9 in complex with haptoglobin-hemoglobin | electron microscopy | C | NAG, CA | 4 (best 0.75) |
| P00738 | AlphaFold monomer V2.0 prediction for haptoglobin (P00738) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5HU6 chain C against the predicted model P00738: TM-score 0.99, RMSD 0.58 Å
- 5HU6 chain C against the predicted model P00738: TM-score 0.99, RMSD 0.58 Å
- 6TB2 chain C against the predicted model P00738: TM-score 0.98, RMSD 0.82 Å
- 9FHB chain C against the predicted model P00738: TM-score 0.98, RMSD 0.97 Å
- 9FMU chain C against the predicted model P00738: TM-score 0.97, RMSD 1.00 Å
- 8XMP chain 2 against the predicted model P00738: TM-score 0.97, RMSD 1.16 Å
- 8XMW chain 2 against the predicted model P00738: TM-score 0.97, RMSD 1.17 Å
- 4X0L chain C against the predicted model P00738: TM-score 0.96, RMSD 1.61 Å
- 4X0L chain C against the predicted model P00738: TM-score 0.96, RMSD 1.61 Å
- 4WJG chain W against the predicted model P00738: TM-score 0.93, RMSD 2.19 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.