UniProt P00505
Aspartate aminotransferase, mitochondrial (P00505)
Aspartate aminotransferase, mitochondrial (UniProt P00505), EC 2.6.1.1, 2.6.1.7: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against…
- UniProt
- P00505
- Protein
- Aspartate aminotransferase, mitochondrial
- EC
- 2.6.1.1, 2.6.1.7
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 1 record with a druggable one
Structures
3 records of P00505 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5AX8 | Recombinant expression, purification and preliminary crystallographic studies of the mature form of… | x-ray diffraction | A, B, C, D | — | — |
| 8SKR | human liver mitochondrial Aspartate aminotransferase | electron microscopy | A, C | PLP | 10 (best 0.74) |
| P00505 | AlphaFold monomer V2.0 prediction for aspartate aminotransferase, mitochondrial (P00505) | predicted | A | — | — |
Ligands
- PLP · Pyridoxal-5'-phosphate · in 1 record
Experiment against prediction
- 5AX8 chain A against the predicted model P00505: TM-score 1.00, RMSD 0.50 Å
- 5AX8 chain B against the predicted model P00505: TM-score 1.00, RMSD 0.51 Å
- 5AX8 chain C against the predicted model P00505: TM-score 1.00, RMSD 0.51 Å
- 5AX8 chain D against the predicted model P00505: TM-score 0.99, RMSD 0.56 Å
- 8SKR chain C against the predicted model P00505: TM-score 0.99, RMSD 0.72 Å
- 8SKR chain A against the predicted model P00505: TM-score 0.99, RMSD 0.72 Å
Elsewhere
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