UniProt P00497
Glutamine phosphoribosylpyrophosphate amidotransferase (P00497)
Glutamine phosphoribosylpyrophosphate amidotransferase (UniProt P00497), EC 2.4.2.14: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 24 pockets. Binding sites, druggability and experiment against…
- UniProt
- P00497
- Protein
- Glutamine phosphoribosylpyrophosphate amidotransferase
- EC
- 2.4.2.14
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 24 · 2 records with a druggable one
Structures
5 records of P00497 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AO0 | Glutamine phosphoribosylpyrophosphate (prpp) amidotransferase from B. subtilis complexed with ADP… | x-ray diffraction | A, B, C, D | MG, SF4, 5GP, ADP | 20 (best 0.88) |
| 1AO0 | Glutamine phosphoribosylpyrophosphate (prpp) amidotransferase from B. subtilis complexed with ADP… | x-ray diffraction | A, B, C, D | — | — |
| 1GPH | Structure of the allosteric regulatory enzyme of purine biosynthesis | x-ray diffraction | 1, 2, 3, 4 | — | — |
| 1GPH | Structure of the allosteric regulatory enzyme of purine biosynthesis | x-ray diffraction | 1, 2, 3, 4 | — | — |
| P00497 | AlphaFold monomer V2.0 prediction for amidophosphoribosyltransferase (P00497) | predicted | A | — | 4 (best 0.80) |
Ligands
Experiment against prediction
- 1GPH chain 1 against the predicted model P00497: TM-score 0.98, RMSD 1.26 Å
- 1GPH chain 1 against the predicted model P00497: TM-score 0.98, RMSD 1.26 Å
- 1AO0 chain A against the predicted model P00497: TM-score 0.98, RMSD 1.30 Å
- 1AO0 chain A against the predicted model P00497: TM-score 0.98, RMSD 1.30 Å
Elsewhere
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