UniProt P00427
Cytochrome c oxidase subunit 6, mitochondrial (P00427)
Cytochrome c oxidase subunit 6, mitochondrial (UniProt P00427), EC 1.9.3.1: 16 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P00427
- Protein
- Cytochrome c oxidase subunit 6, mitochondrial
- EC
- 1.9.3.1
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 21 · 8 records with a druggable one
Structures
17 records of P00427 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GIQ | Saccharomyces cerevisiae respiratory supercomplex III2IV | electron microscopy | f | — | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | f, r | — | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | f, r | — | — |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | f, s | PEF | 2 (best 0.79) |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | f, s | PEF | — |
| 6T15 | The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae | electron microscopy | f | — | — |
| 6YMX | CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | f | PTY | 1 (best 0.82) |
| 6YMX | CIII2/CIV respiratory supercomplex from saccharomyces cerevisiae | electron microscopy | f | PTY | — |
| 6YMY | Cytochrome c oxidase from Saccharomyces cerevisiae | electron microscopy | f | — | 4 (best 0.77) |
| 6YMY | Cytochrome C oxidase from saccharomyces cerevisiae | electron microscopy | f | — | — |
| 7Z10 | Monomeric respiratory complex IV isolated from S. cerevisiae | electron microscopy | f | — | 4 (best 0.71) |
| 8DH6 | Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid… | electron microscopy | f | — | 6 (best 0.78) |
| 8DH6 | Cryo-EM structure of saccharomyces cerevisiae cytochrome C oxidase (complex IV) extracted in lipid… | electron microscopy | f | — | — |
| 8E7S | III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 | electron microscopy | Q, q | — | 2 (best 0.90) |
| 8EC0 | III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant | electron microscopy | Q | — | 1 (best 0.85) |
| 9ETZ | III2IV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | f | — | 1 (best 0.81) |
| P00427 | AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 6, mitochondrial (P00427) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6T0B chain s against the predicted model P00427: TM-score 0.99, RMSD 0.44 Å
- 6T0B chain s against the predicted model P00427: TM-score 0.99, RMSD 0.44 Å
- 6HU9 chain r against the predicted model P00427: TM-score 0.98, RMSD 0.52 Å
- 6HU9 chain r against the predicted model P00427: TM-score 0.98, RMSD 0.52 Å
- 8DH6 chain f against the predicted model P00427: TM-score 0.98, RMSD 0.53 Å
- 8DH6 chain f against the predicted model P00427: TM-score 0.98, RMSD 0.53 Å
- 6HU9 chain f against the predicted model P00427: TM-score 0.98, RMSD 0.54 Å
- 6HU9 chain f against the predicted model P00427: TM-score 0.98, RMSD 0.54 Å
- 6T0B chain f against the predicted model P00427: TM-score 0.98, RMSD 0.68 Å
- 6T0B chain f against the predicted model P00427: TM-score 0.98, RMSD 0.68 Å
Elsewhere
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