UniProt P00420
Cytochrome c oxidase subunit 3 (P00420)
Cytochrome c oxidase subunit 3 (UniProt P00420), EC 1.9.3.1, 7.1.1.9: 16 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 35 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P00420
- Protein
- Cytochrome c oxidase subunit 3
- EC
- 1.9.3.1, 7.1.1.9
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 35 · 8 records with a druggable one
Structures
17 records of P00420 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GIQ | Saccharomyces cerevisiae respiratory supercomplex III2IV | electron microscopy | c | — | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | c, o | PEF | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | c, o | PEF | — |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | c, p | PEF | 2 (best 0.83) |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | c, p | PEF | — |
| 6T15 | The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae | electron microscopy | c | PEF | — |
| 6YMX | CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | c | PTY, PCF | 1 (best 0.84) |
| 6YMX | CIII2/CIV respiratory supercomplex from saccharomyces cerevisiae | electron microscopy | c | PTY, PCF | — |
| 6YMY | Cytochrome c oxidase from Saccharomyces cerevisiae | electron microscopy | c | PTY, PCF | 10 (best 0.83) |
| 6YMY | Cytochrome C oxidase from saccharomyces cerevisiae | electron microscopy | c | PTY, PCF | — |
| 7Z10 | Monomeric respiratory complex IV isolated from S. cerevisiae | electron microscopy | c | PEF | 8 (best 0.82) |
| 8DH6 | Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid… | electron microscopy | c | PEF | 6 (best 0.84) |
| 8DH6 | Cryo-EM structure of saccharomyces cerevisiae cytochrome C oxidase (complex IV) extracted in lipid… | electron microscopy | c | PEF | — |
| 8E7S | III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 | electron microscopy | O, o | — | 5 (best 0.89) |
| 8EC0 | III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant | electron microscopy | O | — | 2 (best 0.88) |
| 9ETZ | III2IV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | c | PEF, CDL | 1 (best 0.83) |
| P00420 | AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 3 (P00420) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8DH6 chain c against the predicted model P00420: TM-score 0.97, RMSD 1.22 Å
- 8DH6 chain c against the predicted model P00420: TM-score 0.97, RMSD 1.22 Å
- 6HU9 chain c against the predicted model P00420: TM-score 0.97, RMSD 1.25 Å
- 6HU9 chain c against the predicted model P00420: TM-score 0.97, RMSD 1.25 Å
- 6HU9 chain o against the predicted model P00420: TM-score 0.97, RMSD 1.26 Å
- 6HU9 chain o against the predicted model P00420: TM-score 0.97, RMSD 1.26 Å
- 6T0B chain c against the predicted model P00420: TM-score 0.97, RMSD 1.28 Å
- 6T0B chain c against the predicted model P00420: TM-score 0.97, RMSD 1.28 Å
- 6T15 chain c against the predicted model P00420: TM-score 0.96, RMSD 1.31 Å
- 6YMY chain c against the predicted model P00420: TM-score 0.96, RMSD 1.30 Å
Elsewhere
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