UniProt O95866
Megakaryocyte and platelet inhibitory receptor G6b (O95866)
Megakaryocyte and platelet inhibitory receptor G6b (UniProt O95866): 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O95866
- Protein
- Megakaryocyte and platelet inhibitory receptor G6b
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of O95866 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6R0X | The extracellular domain of G6b-B in complex with Fab fragment and DP12 heparin oligosaccharide. | x-ray diffraction | E, F | A2G, SGN, IDS, GAL | 5 (best 0.64) |
| 6R0X | The extracellular domain of G6B-B in complex with Fab fragment and DP12 heparin oligosaccharide. | x-ray diffraction | E, F | A2G, SGN, IDS, GAL | — |
| O95866 | AlphaFold monomer V2.0 prediction for megakaryocyte and platelet inhibitory receptor G6B (O95866) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6R0X chain E against the predicted model O95866: TM-score 0.91, RMSD 1.41 Å
- 6R0X chain E against the predicted model O95866: TM-score 0.91, RMSD 1.41 Å
- 6R0X chain F against the predicted model O95866: TM-score 0.88, RMSD 1.73 Å
- 6R0X chain F against the predicted model O95866: TM-score 0.88, RMSD 1.73 Å
Elsewhere
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