UniProt O95622
Adenylate cyclase type 5 (O95622)
Adenylate cyclase type 5 (UniProt O95622), EC 4.6.1.1: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O95622
- Protein
- Adenylate cyclase type 5
- EC
- 4.6.1.1
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 34 · 2 records with a druggable one
Structures
3 records of O95622 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8SL3 | Human adenylyl Cyclase 5 in complex with Gbg | electron microscopy | A | GER | 14 (best 0.85) |
| 8SL4 | Dimeric form of human adenylyl cyclase 5 | electron microscopy | A, B | — | 20 (best 0.81) |
| O95622 | AlphaFold monomer V2.0 prediction for adenylate cyclase type 5 (O95622) | predicted | A | — | — |
Ligands
- GER · Geran-8-yl geran · in 1 record
Experiment against prediction
- 8SL3 chain A against the predicted model O95622: TM-score 0.96, RMSD 2.05 Å
- 8SL4 chain B against the predicted model O95622: TM-score 0.90, RMSD 3.85 Å
- 8SL4 chain A against the predicted model O95622: TM-score 0.89, RMSD 3.87 Å
Elsewhere
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