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UniProt O95602

DNA-directed RNA polymerase I subunit RPA1 (O95602)

DNA-directed RNA polymerase I subunit RPA1 (UniProt O95602), EC 2.7.7.6: 7 experimental structures on GenesisL1, 3 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
O95602
Protein
DNA-directed RNA polymerase I subunit RPA1
EC
2.7.7.6
Experimental structures
7
Predicted models
0
Ligands
3
Pockets
14 · 1 record with a druggable one

Structures

7 records of O95602 in the MolNFT archive: 7 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7OB9Cryo-EM structure of human RNA polymerase I in elongation stateelectron microscopyAZN, MG—
7OBACryo-EM structure of human RNA polymerase I in complex with RRN3electron microscopyAZN—
7OBBCryo-EM structure of human RNA polymerase I open complexelectron microscopyAZN—
7VBAStructure of the pre state human RNA Polymerase I Elongation Complexelectron microscopyAZN, MG, 2TM—
8A43Human RNA polymerase Ielectron microscopyA—14 (best 0.87)
8A43Human RNA polymerase Ielectron microscopyA——
O95602AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA1 (O95602)———

Ligands

  • ZN · Zinc ion · in 4 records
  • MG · Magnesium ion · in 2 records
  • 2TM · 5'-O-[(S)-hydroxy{[(s)-hydroxy(phosphonooxy) phosphoryl]methyl}phosphoryl]cytidine · in 1 record

Elsewhere

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