UniProt O95477
ATP-binding cassette sub-family A member 1 (O95477)
ATP-binding cassette sub-family A member 1 (UniProt O95477): 3 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O95477
- Protein
- ATP-binding cassette sub-family A member 1
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 20 · 1 record with a druggable one
Structures
4 records of O95477 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XJY | Cryo-EM structure of human ABCA1 | electron microscopy | A | NAG, BMA | 20 (best 0.82) |
| 5XJY | Cryo-EM structure of human ABCA1 | electron microscopy | A | NAG, BMA | — |
| 7ROQ | Alternative structure of human ABCA1 | electron microscopy | A | NAG, POV, CLR | — |
| O95477 | AlphaFold monomer V2.0 prediction for phospholipid-transporting ATPase ABCA1 (O95477) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7ROQ chain A against the predicted model O95477: TM-score 0.72, RMSD 8.04 Å
- 5XJY chain A against the predicted model O95477: TM-score 0.65, RMSD 8.69 Å
- 5XJY chain A against the predicted model O95477: TM-score 0.65, RMSD 8.69 Å
Elsewhere
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