UniProt O88554
Poly [ADP-ribose] polymerase 2 (O88554)
Poly [ADP-ribose] polymerase 2 (UniProt O88554): 2 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O88554
- Protein
- Poly [ADP-ribose] polymerase 2
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
3 records of O88554 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GS0 | Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2 | x-ray diffraction | A, B | — | — |
| 1GS0 | Crystal structure of the catalytic fragment of murine poly (ADP-ribose) polymerase-2 | x-ray diffraction | A, B | — | — |
| O88554 | AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase 2 (O88554) | predicted | A | — | 6 (best 0.76) |
Experiment against prediction
- 1GS0 chain B against the predicted model O88554: TM-score 0.98, RMSD 0.91 Å
- 1GS0 chain B against the predicted model O88554: TM-score 0.98, RMSD 0.91 Å
- 1GS0 chain A against the predicted model O88554: TM-score 0.98, RMSD 0.94 Å
- 1GS0 chain A against the predicted model O88554: TM-score 0.98, RMSD 0.94 Å
Elsewhere
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