UniProt O75943
Cell cycle checkpoint protein RAD1,Cell cycle checkpoint protein RAD17 (O75943)
Cell cycle checkpoint protein RAD1,Cell cycle checkpoint protein RAD17 (UniProt O75943), EC 3.1.11.2: 4 experimental structures on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, pockets, druggability and 3D structures in…
- UniProt
- O75943
- Protein
- Cell cycle checkpoint protein RAD1,Cell cycle checkpoint protein RAD17
- EC
- 3.1.11.2
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
4 records of O75943 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7Z6H | Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp | electron microscopy | B, K | AGS | 10 (best 0.85) |
| 7Z6H | Structure of DNA-bound human RAD17-rfc clamp loader and 9-1-1 checkpoint clamp | electron microscopy | B, K | AGS | — |
| 8GNN | Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex | x-ray diffraction | D | — | 1 (best 0.46) |
| O75943 | AlphaFold monomer V2.0 prediction for cell cycle checkpoint protein RAD17 (O75943) | — | — | — |
Ligands
- AGS · Phosphothiophosphoric acid-adenylate ester · in 2 records
Experiment against prediction
- 7Z6H chain B against the predicted model O60671: TM-score 0.96, RMSD 1.18 Å
- 7Z6H chain B against the predicted model O60671: TM-score 0.96, RMSD 1.18 Å
- 7Z6H chain K against the predicted model O60671: TM-score 0.18, RMSD 6.07 Å
- 7Z6H chain K against the predicted model O60671: TM-score 0.18, RMSD 6.07 Å
Elsewhere
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