UniProt O75886
Signal transducing adapter molecule 2 (O75886)
Signal transducing adapter molecule 2 (UniProt O75886): 9 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75886
- Protein
- Signal transducing adapter molecule 2
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 5 · 0 records with a druggable one
Structures
10 records of O75886 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1X2Q | Solution structure of the SH3 domain of the Signal transducing adaptor molecule 2 | solution nmr | A | — | — |
| 1X2Q | Solution structure of the SH3 domain of the signal transducing adaptor molecule 2 | solution nmr | A | — | — |
| 1X5B | The solution structure of the VHS domain of human Signal transducing adaptor molecule 2 | solution nmr | A | — | — |
| 1X5B | The solution structure of the vhs domain of human signal transducing adaptor molecule 2 | solution nmr | A | — | — |
| 2L0T | Solution structure of the complex of ubiquitin and the VHS domain of Stam2 | solution nmr | B | — | 1 (best 0.40) |
| 2L0T | Solution structure of the complex of ubiquitin and the vhs domain of STAM2 | solution nmr | B | — | 1 (best 0.40) |
| 5CRV | Crystal structure of the bro domain of hd-ptp in a complex with the core region of STAM2 | x-ray diffraction | C, D | — | 2 (best 0.49) |
| 5IXF | Solution structure of the STAM2 SH3 with AMSH derived peptide complex | solution nmr | A | — | — |
| 5IXF | Solution structure of the STAM2 SH3 with amsh derived peptide complex | solution nmr | A | — | — |
| O75886 | AlphaFold monomer V2.0 prediction for signal transducing adapter molecule 2 (O75886) | predicted | A | — | 1 (best 0.32) |
Experiment against prediction
- 1X5B chain A against the predicted model O75886: TM-score 0.89, RMSD 1.88 Å
- 1X5B chain A against the predicted model O75886: TM-score 0.89, RMSD 1.88 Å
- 2L0T chain B against the predicted model O75886: TM-score 0.87, RMSD 1.80 Å
- 2L0T chain B against the predicted model O75886: TM-score 0.87, RMSD 1.80 Å
- 5IXF chain A against the predicted model O75886: TM-score 0.82, RMSD 1.85 Å
- 5IXF chain A against the predicted model O75886: TM-score 0.82, RMSD 1.85 Å
- 1X2Q chain A against the predicted model O75886: TM-score 0.64, RMSD 1.83 Å
- 1X2Q chain A against the predicted model O75886: TM-score 0.64, RMSD 1.83 Å
- 5CRV chain C against the predicted model O75886: TM-score 0.49, RMSD 0.81 Å
- 5CRV chain D against the predicted model O75886: TM-score 0.47, RMSD 2.03 Å
Elsewhere
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