UniProt O75822
Eukaryotic translation initiation factor 3 subunit J (O75822)
Eukaryotic translation initiation factor 3 subunit J (UniProt O75822): 7 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75822
- Protein
- Eukaryotic translation initiation factor 3 subunit J
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
8 records of O75822 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KRB | Solution structure of EIF3B-RRM bound to EIF3J peptide | solution nmr | B | — | — |
| 2KRB | Solution structure of EIF3B-rrm bound to EIF3J peptide | solution nmr | B | — | — |
| 3BPJ | Crystal structure of human translation initiation factor 3, subunit 1 alpha | x-ray diffraction | A, B, C, D | — | — |
| 3BPJ | Crystal structure of human translation initiation factor 3, subunit 1 alpha | x-ray diffraction | A, B, C, D | — | — |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | z | — | 1 (best 0.86) |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | z | — | — |
| 6ZVJ | Structure of a human ABCE1-bound 43S pre-initiation complex - State II | electron microscopy | G, J | — | — |
| O75822 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit J (O75822) | predicted | A | — | — |
Experiment against prediction
- 3BPJ chain D against the predicted model O75822: TM-score 0.97, RMSD 0.54 Å
- 3BPJ chain D against the predicted model O75822: TM-score 0.97, RMSD 0.54 Å
- 3BPJ chain C against the predicted model O75822: TM-score 0.95, RMSD 0.67 Å
- 3BPJ chain C against the predicted model O75822: TM-score 0.95, RMSD 0.67 Å
- 3BPJ chain A against the predicted model O75822: TM-score 0.95, RMSD 0.68 Å
- 3BPJ chain A against the predicted model O75822: TM-score 0.95, RMSD 0.68 Å
- 6ZVJ chain J against the predicted model O75822: TM-score 0.93, RMSD 0.86 Å
- 6ZVJ chain G against the predicted model O75822: TM-score 0.93, RMSD 0.82 Å
- 3BPJ chain B against the predicted model O75822: TM-score 0.92, RMSD 1.12 Å
- 3BPJ chain B against the predicted model O75822: TM-score 0.92, RMSD 1.12 Å
Elsewhere
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