UniProt O75817
Ribonuclease P protein subunit p20 (O75817)
Ribonuclease P protein subunit p20 (UniProt O75817), EC 3.1.26.5: 8 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75817
- Protein
- Ribonuclease P protein subunit p20
- EC
- 3.1.26.5
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 16 · 3 records with a druggable one
Structures
9 records of O75817 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AHR | Cryo-EM structure of human Ribonuclease P | electron microscopy | G | — | 4 (best 0.87) |
| 6AHR | Cryo-EM structure of human ribonuclease P | electron microscopy | G | — | — |
| 6AHU | Cryo-EM structure of human Ribonuclease P with mature tRNA | electron microscopy | G | — | 5 (best 0.88) |
| 6AHU | Cryo-EM structure of human ribonuclease P with mature tRNA | electron microscopy | G | — | — |
| 6CWX | Crystal structure of human ribonuclease P/MRP proteins Rpp20/Rpp25 | x-ray diffraction | A | — | — |
| 6CWX | Crystal structure of human ribonuclease P/MRP proteins RPP20/RPP25 | x-ray diffraction | A | — | — |
| 6LT7 | Crystal structure of human RPP20-RPP25 proteins in complex with the P3 domain of lncRNA RMRP | x-ray diffraction | A, D | — | 6 (best 0.74) |
| 6LT7 | Crystal structure of human RPP20-RPP25 proteins in complex with the P3 domain of lncrna rmrp | x-ray diffraction | A, D | — | — |
| O75817 | AlphaFold monomer V2.0 prediction for ribonuclease P protein subunit P20 (O75817) | predicted | A | — | 1 (best 0.48) |
Experiment against prediction
- 6CWX chain A against the predicted model O75817: TM-score 0.89, RMSD 1.72 Å
- 6CWX chain A against the predicted model O75817: TM-score 0.89, RMSD 1.72 Å
- 6LT7 chain D against the predicted model O75817: TM-score 0.87, RMSD 2.03 Å
- 6LT7 chain A against the predicted model O75817: TM-score 0.86, RMSD 1.85 Å
- 6LT7 chain A against the predicted model O75817: TM-score 0.86, RMSD 1.85 Å
- 6AHU chain G against the predicted model O75817: TM-score 0.83, RMSD 2.11 Å
- 6AHU chain G against the predicted model O75817: TM-score 0.83, RMSD 2.11 Å
- 6AHR chain G against the predicted model O75817: TM-score 0.82, RMSD 2.15 Å
- 6AHR chain G against the predicted model O75817: TM-score 0.82, RMSD 2.15 Å
Elsewhere
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