UniProt O75575
DNA-directed RNA polymerase III subunit RPC9 (O75575)
DNA-directed RNA polymerase III subunit RPC9 (UniProt O75575): 24 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75575
- Protein
- DNA-directed RNA polymerase III subunit RPC9
- Experimental structures
- 24
- Predicted models
- 1
- Pockets
- 7 · 6 records with a druggable one
Structures
25 records of O75575 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7A6H | Cryo-EM structure of human apo RNA Polymerase III | electron microscopy | D | — | 1 (best 0.73) |
| 7A6H | Cryo-EM structure of human apo RNA polymerase III | electron microscopy | D | — | — |
| 7AE1 | Cryo-EM structure of human RNA Polymerase III elongation complex 1 | electron microscopy | D | — | — |
| 7AE1 | Cryo-EM structure of human RNA polymerase III elongation complex 1 | electron microscopy | D | — | — |
| 7AE3 | Cryo-EM structure of human RNA Polymerase III elongation complex 3 | electron microscopy | D | — | — |
| 7AE3 | Cryo-EM structure of human RNA polymerase III elongation complex 3 | electron microscopy | D | — | — |
| 7AEA | Cryo-EM structure of human RNA Polymerase III elongation complex 2 | electron microscopy | D | — | 1 (best 0.78) |
| 7AEA | Cryo-EM structure of human RNA polymerase III elongation complex 2 | electron microscopy | D | — | — |
| 7AST | Apo Human RNA Polymerase III | electron microscopy | I | — | 2 (best 0.79) |
| 7AST | Apo human RNA polymerase III | electron microscopy | I | — | — |
| 7D58 | cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | D | — | — |
| 7D58 | Cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | D | — | — |
| 7D59 | cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | D | — | — |
| 7D59 | Cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | D | — | — |
| 7DN3 | Structure of Human RNA Polymerase III elongation complex | electron microscopy | D | — | — |
| 7DN3 | Structure of human RNA polymerase III elongation complex | electron microscopy | D | — | — |
| 7DU2 | RNA polymerase III ec complex in post-translocation state | electron microscopy | D | — | — |
| 7FJI | human Pol III elongation complex | electron microscopy | D | — | — |
| 7FJI | Human pol III elongation complex | electron microscopy | D | — | — |
| 7FJJ | human Pol III pre-termination complex | electron microscopy | D | — | — |
| 7FJJ | Human pol III pre-termination complex | electron microscopy | D | — | — |
| 8ITY | human RNA polymerase III pre-initiation complex closed DNA 1 | electron microscopy | D | — | 1 (best 0.78) |
| 8IUE | RNA polymerase III pre-initiation complex melting complex 1 | electron microscopy | D | — | 1 (best 0.77) |
| 8IUH | RNA polymerase III pre-initiation complex open complex 1 | electron microscopy | D | — | 1 (best 0.77) |
| O75575 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC9 (O75575) | predicted | A | — | — |
Experiment against prediction
- 7A6H chain D against the predicted model O75575: TM-score 0.91, RMSD 1.35 Å
- 7A6H chain D against the predicted model O75575: TM-score 0.91, RMSD 1.35 Å
- 7AE3 chain D against the predicted model O75575: TM-score 0.90, RMSD 1.45 Å
- 7AE3 chain D against the predicted model O75575: TM-score 0.90, RMSD 1.45 Å
- 7AE1 chain D against the predicted model O75575: TM-score 0.89, RMSD 1.53 Å
- 7AE1 chain D against the predicted model O75575: TM-score 0.89, RMSD 1.53 Å
- 7AEA chain D against the predicted model O75575: TM-score 0.89, RMSD 1.55 Å
- 7AEA chain D against the predicted model O75575: TM-score 0.89, RMSD 1.55 Å
- 7D58 chain D against the predicted model O75575: TM-score 0.88, RMSD 1.65 Å
- 7D58 chain D against the predicted model O75575: TM-score 0.88, RMSD 1.65 Å
Elsewhere
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