UniProt O75390
Citrate synthase, mitochondrial (O75390)
Citrate synthase, mitochondrial (UniProt O75390), EC 2.3.3.1: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O75390
- Protein
- Citrate synthase, mitochondrial
- EC
- 2.3.3.1
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 2 records with a druggable one
Structures
5 records of O75390 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UZP | Crystal structure of citrate synthase mutant A348G from homo sapiens | x-ray diffraction | A, B | OAA | 7 (best 0.70) |
| 5UZP | Crystal structure of citrate synthase mutant A348G from homo sapiens | x-ray diffraction | A, B | OAA | — |
| 5UZR | Crystal structure of citrate synthase from homo sapiens | x-ray diffraction | A, D | CL | 8 (best 0.70) |
| 5UZR | Crystal structure of citrate synthase from homo sapiens | x-ray diffraction | A, D | CL | — |
| O75390 | AlphaFold monomer V2.0 prediction for citrate synthase, mitochondrial (O75390) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5UZR chain A against the predicted model O75390: TM-score 1.00, RMSD 0.32 Å
- 5UZR chain A against the predicted model O75390: TM-score 1.00, RMSD 0.32 Å
- 5UZR chain D against the predicted model O75390: TM-score 1.00, RMSD 0.33 Å
- 5UZR chain D against the predicted model O75390: TM-score 1.00, RMSD 0.33 Å
- 5UZP chain A against the predicted model O75390: TM-score 0.99, RMSD 0.61 Å
- 5UZP chain A against the predicted model O75390: TM-score 0.99, RMSD 0.61 Å
- 5UZP chain B against the predicted model O75390: TM-score 0.99, RMSD 0.68 Å
- 5UZP chain B against the predicted model O75390: TM-score 0.99, RMSD 0.68 Å
Elsewhere
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