UniProt O75351
Vacuolar protein sorting-associated protein 4B (O75351)
Vacuolar protein sorting-associated protein 4B (UniProt O75351): 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O75351
- Protein
- Vacuolar protein sorting-associated protein 4B
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 1 record with a druggable one
Structures
14 records of O75351 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WR0 | Structural characterization of the MIT domain from human Vps4b | solution nmr | A | — | — |
| 1WR0 | Structural characterization of the mit domain from human VPS4B | solution nmr | A | — | — |
| 1XWI | Crystal Structure of VPS4B | x-ray diffraction | A | — | — |
| 1XWI | Crystal structure of VPS4B | x-ray diffraction | A | — | — |
| 2CPT | Solution structure of MIT domain from human SKD1 | solution nmr | A | — | — |
| 2CPT | Solution structure of mit domain from human SKD1 | solution nmr | A | — | — |
| 2JQH | VPS4B MIT | solution nmr | A | — | — |
| 2JQH | VPS4B MIT | solution nmr | A | — | — |
| 2JQK | VPS4B MIT-CHMP2B Complex | solution nmr | A | — | — |
| 2JQK | VPS4B mit-CHMP2B complex | solution nmr | A | — | — |
| 4U7Y | Structure of the complex of VPS4B MIT and IST1 MIM | x-ray diffraction | A | — | — |
| 4U7Y | Structure of the complex of VPS4B mit and IST1 mim | x-ray diffraction | A | — | — |
| 7L9X | Structure of VPS4B in complex with an allele-specific covalent inhibitor | x-ray diffraction | A | XQV, SO4 | — |
| O75351 | AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 4B (O75351) | predicted | A | — | 2 (best 0.53) |
Ligands
Experiment against prediction
- 1XWI chain A against the predicted model O75351: TM-score 0.94, RMSD 1.86 Å
- 1XWI chain A against the predicted model O75351: TM-score 0.94, RMSD 1.86 Å
- 4U7Y chain A against the predicted model O75351: TM-score 0.93, RMSD 0.98 Å
- 4U7Y chain A against the predicted model O75351: TM-score 0.93, RMSD 0.98 Å
- 7L9X chain A against the predicted model O75351: TM-score 0.93, RMSD 1.73 Å
- 2JQK chain A against the predicted model O75351: TM-score 0.90, RMSD 1.06 Å
- 2JQK chain A against the predicted model O75351: TM-score 0.90, RMSD 1.06 Å
- 2JQH chain A against the predicted model O75351: TM-score 0.89, RMSD 1.25 Å
- 2JQH chain A against the predicted model O75351: TM-score 0.89, RMSD 1.25 Å
- 1WR0 chain A against the predicted model O75351: TM-score 0.82, RMSD 1.88 Å
Elsewhere
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