UniProt O60939
Sodium channel subunit beta-2 (O60939)
Sodium channel subunit beta-2 (UniProt O60939): 47 experimental structures on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O60939
- Protein
- Sodium channel subunit beta-2
- Experimental structures
- 47
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 14 · 6 records with a druggable one
Structures
47 records of O60939 in the MolNFT archive: 47 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FDY | Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain… | x-ray diffraction | A, B | — | — |
| 5FDY | Crystal structure of the voltage-gated sodium channel beta 2 subunit extracellular domain… | x-ray diffraction | A, B | — | — |
| 5FEB | Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain | x-ray diffraction | A | — | — |
| 5FEB | Crystal structure of the voltage-gated sodium channel beta 2 subunit extracellular domain | x-ray diffraction | A | — | — |
| 6J8E | Human Nav1.2-beta2-KIIIA ternary complex | electron microscopy | C | — | 1 (best 0.69) |
| 6J8E | Human NAV1.2-BETA2-kiiia ternary complex | electron microscopy | C | — | — |
| 6J8G | Structure of human voltage-gated sodium channel Nav1.7 in complex with auxiliary beta subunits… | electron microscopy | C | NAG | — |
| 6J8G | Structure of human voltage-gated sodium channel NAV1.7 in complex with auxiliary beta subunits… | electron microscopy | C | NAG | — |
| 6J8H | Structure of human voltage-gated sodium channel Nav1.7 in complex with auxiliary beta subunits… | electron microscopy | C | NAG | — |
| 6J8H | Structure of human voltage-gated sodium channel NAV1.7 in complex with auxiliary beta subunits… | electron microscopy | C | NAG | — |
| 6J8I | Structure of human voltage-gated sodium channel Nav1.7 in complex with auxiliary beta subunits… | electron microscopy | C | NAG | 1 (best 0.47) |
| 6J8I | Structure of human voltage-gated sodium channel NAV1.7 in complex with auxiliary beta subunits… | electron microscopy | C | NAG | — |
| 6J8J | Structure of human voltage-gated sodium channel NAV1.7 in complex with auxiliary beta subunits… | electron microscopy | C | NAG | — |
| 6VRR | Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 2 subunit… | x-ray diffraction | A | — | — |
| 6VRR | Crystal structure of a disease mutant of the voltage-gated sodium channel beta 2 subunit… | x-ray diffraction | A | — | — |
| 7W77 | cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA | electron microscopy | C | — | 1 (best 0.63) |
| 7W77 | Cryo-EM structure of human NAV1.3/BETA1/BETA2-bulleyaconitinea | electron microscopy | C | — | — |
| 7W7F | Cryo-EM structure of human NAV1.3/BETA1/BETA2-ICA121431 | electron microscopy | C | — | — |
| 7W9K | Cryo-EM structure of human Nav1.7-beta1-beta2 complex at 2.2 angstrom resolution | electron microscopy | C | — | — |
| 7W9K | Cryo-EM structure of human NAV1.7-BETA1-BETA2 complex at 2.2 ångström resolution | electron microscopy | C | — | — |
| 7W9L | Cryo-EM structure of human Nav1.7(E406K)-beta1-beta2 complex | electron microscopy | C | — | 1 (best 0.45) |
| 7W9L | Cryo-EM structure of human NAV1.7(E406K)-BETA1-BETA2 complex | electron microscopy | C | — | — |
| 7W9M | Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, ProTx-II and… | electron microscopy | C | — | — |
| 7W9M | Cryo-EM structure of human NAV1.7(E406K) in complex with auxiliary beta subunits, protx-II and… | electron microscopy | C | — | — |
| 7W9P | Cryo-EM structure of human NAV1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and… | electron microscopy | C | — | — |
| 7W9T | Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and… | electron microscopy | C | — | 1 (best 0.48) |
| 7W9T | Cryo-EM structure of human NAV1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and… | electron microscopy | C | — | — |
| 7XM9 | Cryo-EM structure of human NaV1.7/beta1/beta2-XEN907 | electron microscopy | C | — | 1 (best 0.47) |
| 7XMF | Cryo-EM structure of human NaV1.7/beta1/beta2-Nav1.7-IN2 | electron microscopy | C | — | 2 (best 0.56) |
| 7XMG | Cryo-EM structure of human NaV1.7/beta1/beta2-TCN-1752 | electron microscopy | F | — | 2 (best 0.55) |
| 7XVE | Human Nav1.7 mutant class-I | electron microscopy | C | NAG | 1 (best 0.64) |
| 7XVE | Human NAV1.7 mutant class-I | electron microscopy | C | NAG | — |
| 7XVF | Nav1.7 mutant class2 | electron microscopy | C | NAG | — |
| 7XVF | NAV1.7 mutant CLASS2 | electron microscopy | C | NAG | — |
| 8G1A | Cryo-EM structure of Nav1.7 with CBD | electron microscopy | C | — | — |
| 8GZ1 | Cryo-EM structure of human NaV1.6/beta1/beta2,apo state | electron microscopy | C | — | — |
| 8GZ2 | Cryo-EM structure of human NaV1.6/beta1/beta2-4,9-anhydro-tetrodotoxin | electron microscopy | C | — | 2 (best 0.64) |
| 8I5G | Structure of human Nav1.7 in complex with PF-05089771 | electron microscopy | C | — | — |
| 8I5X | Structure of human Nav1.7 in complex with Vinpocetine | electron microscopy | C | — | — |
| 8I5Y | Structure of human Nav1.7 in complex with vixotrigine | electron microscopy | C | — | — |
| 8S9B | Cryo-EM structure of Nav1.7 with LCM | electron microscopy | C | — | — |
| 8S9C | Cryo-EM structure of Nav1.7 with CBZ | electron microscopy | C | — | — |
| 8THG | Cryo-EM structure of Nav1.7 with RLZ | electron microscopy | C | — | — |
| 8THH | Cryo-EM structure of Nav1.7 with LTG | electron microscopy | C | — | — |
| 8XMN | Voltage-gated sodium channel Nav1.7 variant M2 | electron microscopy | C | — | 1 (best 0.48) |
| 8XMO | Voltage-gated sodium channel Nav1.7 variant M4 | electron microscopy | C | — | — |
| O60939 | AlphaFold monomer V2.0 prediction for sodium channel subunit beta-2 (O60939) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 11 records
Elsewhere
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