UniProt O60870
DNA/RNA-binding protein KIN17 (O60870)
DNA/RNA-binding protein KIN17 (UniProt O60870): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60870
- Protein
- DNA/RNA-binding protein KIN17
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 2 records with a druggable one
Structures
11 records of O60870 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CKK | High resolution crystal structure of the human kin17 C-terminal domain containing a kow motif | x-ray diffraction | A | IOD | 1 (best 0.28) |
| 2CKK | High resolution crystal structure of the human KIN17 C-terminal domain containing a kow motif | x-ray diffraction | A | — | — |
| 2V1N | Solution structure of the region 51-160 of human KIN17 reveals a winged helix fold | solution nmr | A | — | — |
| 2V1N | Solution structure of the region 51-160 of human KIN17 reveals a winged helix fold | solution nmr | A | — | — |
| 7ABH | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | electron microscopy | 7 | — | 1 (best 0.71) |
| 7ABH | Human pre-bact-2 spliceosome (SF3B/U2 snrnp portion) | electron microscopy | 7 | — | — |
| 7ABI | Human pre-Bact-2 spliceosome | electron microscopy | 7 | — | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | 7 | — | — |
| 8I0P | The cryo-EM structure of human pre-Bact complex | electron microscopy | K | ZN | 1 (best 0.87) |
| 9COJ | SH3-like tandem domain of human KIN protein | solution nmr | A | — | — |
| O60870 | AlphaFold monomer V2.0 prediction for DNA/RNA-binding protein KIN17 (O60870) | predicted | A | — | 2 (best 0.33) |
Ligands
Experiment against prediction
- 2CKK chain A against the predicted model O60870: TM-score 0.99, RMSD 0.44 Å
- 2CKK chain A against the predicted model O60870: TM-score 0.99, RMSD 0.44 Å
- 9COJ chain A against the predicted model O60870: TM-score 0.90, RMSD 1.45 Å
- 7ABH chain 7 against the predicted model O60870: TM-score 0.88, RMSD 0.63 Å
- 7ABH chain 7 against the predicted model O60870: TM-score 0.88, RMSD 0.63 Å
- 2V1N chain A against the predicted model O60870: TM-score 0.66, RMSD 2.90 Å
- 2V1N chain A against the predicted model O60870: TM-score 0.66, RMSD 2.90 Å
- 7ABI chain 7 against the predicted model O60870: TM-score 0.51, RMSD 0.47 Å
- 7ABI chain 7 against the predicted model O60870: TM-score 0.51, RMSD 0.47 Å
- 8I0P chain K against the predicted model O60870: TM-score 0.43, RMSD 3.74 Å
Elsewhere
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