UniProt O60741
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (UniProt O60741): 7 experimental structures on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O60741
- Protein
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
- Experimental structures
- 7
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 40 · 2 records with a druggable one
Structures
7 records of O60741 in the MolNFT archive: 7 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5U6O | Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel | electron microscopy | A, B, C, D | — | — |
| 5U6P | Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in… | electron microscopy | A, B, C, D | CMP | 20 (best 0.78) |
| 5U6P | Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in… | electron microscopy | A, B, C, D | CMP | — |
| 6UQF | Human HCN1 channel in a hyperpolarized conformation | electron microscopy | A, B, C, D | CMP, HG | — |
| 6UQG | Human HCN1 channel Y289D mutant | electron microscopy | A, B, C, D | CMP | — |
| 8UC8 | HCN1 nanodisc | electron microscopy | D, C, A, B | PCW | 20 (best 0.77) |
| O60741 | AlphaFold monomer V2.0 prediction for POTASSIUM/SODIUM hyperpolarization-activated cyclic… | — | — | — |
Ligands
Elsewhere
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