UniProt O60508
Pre-mRNA-processing factor 17 (O60508)
Pre-mRNA-processing factor 17 (UniProt O60508): 20 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60508
- Protein
- Pre-mRNA-processing factor 17
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 10 · 4 records with a druggable one
Structures
21 records of O60508 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MQF | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | electron microscopy | E | — | — |
| 5XJC | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | electron microscopy | W | — | — |
| 6FF4 | human Bact spliceosome core structure | electron microscopy | E | — | 1 (best 0.80) |
| 6FF4 | Human bact spliceosome core structure | electron microscopy | E | — | — |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | E | — | — |
| 6ICZ | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 ångström | electron microscopy | W | — | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9… | electron microscopy | W | — | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to PRP43 loaded (ILS1 complex) at 2.9… | electron microscopy | W | — | — |
| 6ID1 | Cryo-EM structure of a human intron lariat spliceosome after PRP43 loaded (ILS2 complex) at 2.9… | electron microscopy | W | — | — |
| 6ZYM | Human C Complex Spliceosome - High-resolution CORE | electron microscopy | E | — | 1 (best 0.77) |
| 6ZYM | Human C complex spliceosome - high-resolution core | electron microscopy | E | — | — |
| 7A5P | Human C Complex Spliceosome - Medium-resolution PERIPHERY | electron microscopy | E | — | — |
| 7A5P | Human C complex spliceosome - medium-resolution periphery | electron microscopy | E | — | — |
| 7AAV | Human pre-bact-2 spliceosome core structure | electron microscopy | 8 | — | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | 8 | — | — |
| 7W59 | The cryo-EM structure of human pre-C*-I complex | electron microscopy | W | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | W | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | W | — | — |
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | o | — | 3 (best 0.84) |
| 8I0U | The cryo-EM structure of human Bact-IV complex | electron microscopy | W | — | — |
| O60508 | AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 17 (O60508) | predicted | A | — | 5 (best 0.78) |
Experiment against prediction
- 7A5P chain E against the predicted model O60508: TM-score 0.98, RMSD 0.94 Å
- 7A5P chain E against the predicted model O60508: TM-score 0.98, RMSD 0.94 Å
- 6ID1 chain W against the predicted model O60508: TM-score 0.91, RMSD 1.65 Å
- 6ZYM chain E against the predicted model O60508: TM-score 0.91, RMSD 1.28 Å
- 6ZYM chain E against the predicted model O60508: TM-score 0.91, RMSD 1.28 Å
- 8C6J chain o against the predicted model O60508: TM-score 0.89, RMSD 2.93 Å
- 6FF4 chain E against the predicted model O60508: TM-score 0.89, RMSD 1.68 Å
- 6FF4 chain E against the predicted model O60508: TM-score 0.89, RMSD 1.68 Å
- 5MQF chain E against the predicted model O60508: TM-score 0.89, RMSD 2.45 Å
- 6ICZ chain W against the predicted model O60508: TM-score 0.88, RMSD 3.07 Å
Elsewhere
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