UniProt O60306
Intron-binding protein aquarius (O60306)
Intron-binding protein aquarius (UniProt O60306), EC 3.6.4.13: 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60306
- Protein
- Intron-binding protein aquarius
- EC
- 3.6.4.13
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
Structures
18 records of O60306 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PJ3 | Structural insight into the function and evolution of the spliceosomal helicase Aquarius, Structure… | x-ray diffraction | A | — | — |
| 4PJ3 | Structural insight into the function and evolution of the spliceosomal helicase aquarius, structure… | x-ray diffraction | A | — | — |
| 5MQF | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | electron microscopy | U | — | — |
| 5XJC | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | electron microscopy | Q | ATP, MG | — |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | U | — | — |
| 6ICZ | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 ångström | electron microscopy | Q | ATP, MG | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9… | electron microscopy | Q | — | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to PRP43 loaded (ILS1 complex) at 2.9… | electron microscopy | Q | — | — |
| 6ID1 | Cryo-EM structure of a human intron lariat spliceosome after PRP43 loaded (ILS2 complex) at 2.9… | electron microscopy | Q | — | — |
| 7A5P | Human C Complex Spliceosome - Medium-resolution PERIPHERY | electron microscopy | U | — | — |
| 7A5P | Human C complex spliceosome - medium-resolution periphery | electron microscopy | U | — | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | U | — | — |
| 7W59 | The cryo-EM structure of human pre-C*-I complex | electron microscopy | Q | ATP, MG | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | Q | ATP, MG | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | Q | ATP, MG | — |
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | U | — | — |
| 8I0U | The cryo-EM structure of human Bact-IV complex | electron microscopy | Q | — | — |
| O60306 | AlphaFold monomer V2.0 prediction for RNA helicase aquarius (O60306) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8C6J chain U against the predicted model O60306: TM-score 0.98, RMSD 1.55 Å
- 5MQF chain U against the predicted model O60306: TM-score 0.98, RMSD 1.55 Å
- 6ID0 chain Q against the predicted model O60306: TM-score 0.98, RMSD 1.67 Å
- 6ID0 chain Q against the predicted model O60306: TM-score 0.98, RMSD 1.67 Å
- 5XJC chain Q against the predicted model O60306: TM-score 0.98, RMSD 1.67 Å
- 6ICZ chain Q against the predicted model O60306: TM-score 0.98, RMSD 1.68 Å
- 6ID1 chain Q against the predicted model O60306: TM-score 0.98, RMSD 1.69 Å
- 4PJ3 chain A against the predicted model O60306: TM-score 0.98, RMSD 1.70 Å
- 4PJ3 chain A against the predicted model O60306: TM-score 0.98, RMSD 1.70 Å
- 8I0U chain Q against the predicted model O60306: TM-score 0.98, RMSD 1.70 Å
Elsewhere
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