UniProt O58328

ADP-dependent glucokinase (O58328)

ADP-dependent glucokinase (UniProt O58328), EC 2.7.1.147: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: O58328
Protein: ADP-dependent glucokinase
EC: 2.7.1.147
Experimental structures: 6
Predicted models: 1
Ligands: 3
Pockets: 4 · 2 records with a druggable one

Structures

7 records of O58328 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
1L2L	Crystal structure of ADP-dependent glucokinase from a Pyrococcus Horikoshii	x-ray diffraction	A	—	—
1L2L	Crystal structure of ADP-dependent glucokinase from a pyrococcus horikoshii	x-ray diffraction	A	—	—
5O0I	ADP-dependent glucokinase from Pyrococcus horikoshii	x-ray diffraction	A	SO4	2 (best 0.74)
5O0I	ADP-dependent glucokinase from pyrococcus horikoshii	x-ray diffraction	A	SO4	—
5O0J	ADP-dependent glucokinase from Pyrococcus horikoshii	x-ray diffraction	A	8BR, GLC	2 (best 0.83)
5O0J	ADP-dependent glucokinase from pyrococcus horikoshii	x-ray diffraction	A	8BR, GLC	—
O58328	AlphaFold monomer V2.0 prediction for ADP-dependent GLUCOSE/GLUCOSAMINE kinase (O58328)	predicted	A	—	—

Ligands

8BR · 8-bromo-adenosine-5'-monophosphate · in 2 records
GLC · alpha-D-glucopyranose · in 2 records
SO4 · Sulfate ion · in 2 records

Experiment against prediction

5O0I chain A against the predicted model O58328: TM-score 0.99, RMSD 0.77 Å
5O0I chain A against the predicted model O58328: TM-score 0.99, RMSD 0.77 Å
1L2L chain A against the predicted model O58328: TM-score 0.94, RMSD 2.05 Å
1L2L chain A against the predicted model O58328: TM-score 0.94, RMSD 2.05 Å
5O0J chain A against the predicted model O58328: TM-score 0.92, RMSD 2.28 Å
5O0J chain A against the predicted model O58328: TM-score 0.92, RMSD 2.28 Å

Elsewhere

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