UniProt O57767
Quinolinate synthase A (O57767)
Quinolinate synthase A (UniProt O57767), EC 2.5.1.72: 25 experimental structures on GenesisL1, 12 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O57767
- Protein
- Quinolinate synthase A
- EC
- 2.5.1.72
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 12
- Pockets
- 5 · 2 records with a druggable one
Structures
25 records of O57767 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WZU | Crystal structure of quinolinate synthase (nadA) | x-ray diffraction | A | — | — |
| 1WZU | Crystal structure of quinolinate synthase (nada) | x-ray diffraction | A | — | — |
| 4ZK6 | Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its… | x-ray diffraction | A, B | — | — |
| 4ZK6 | Crystallographic capture of quinolinate synthase (nada) from pyrococcus horikoshii in its… | x-ray diffraction | A, B | — | — |
| 5KTM | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with a bound Fe4S4 cluster | x-ray diffraction | A | SF4, CL | — |
| 5KTM | Crystal structure of pyrococcus horikoshii quinolinate synthase (nada) with a bound FE4S4 cluster | x-ray diffraction | A | SF4, CL | — |
| 5KTN | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound dihydroxyacetone… | x-ray diffraction | A | SF4, 13P, CL, NH4 | — |
| 5KTN | Crystal structure of pyrococcus horikoshii quinolinate synthase (nada) with bound dihydroxyacetone… | x-ray diffraction | A | SF4, 13P, CL, NH4 | — |
| 5KTO | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound quinolinate and… | x-ray diffraction | A | SF4, NTM, CL | — |
| 5KTO | Crystal structure of pyrococcus horikoshii quinolinate synthase (nada) with bound quinolinate and… | x-ray diffraction | A | SF4, NTM, CL | — |
| 5KTP | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound itaconate and… | x-ray diffraction | A | SF4, CL, ITN, NH4 | 1 (best 0.77) |
| 5KTP | Crystal structure of pyrococcus horikoshii quinolinate synthase (nada) with bound itaconate and… | x-ray diffraction | A | SF4, CL, ITN, NH4 | — |
| 5KTR | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound maleate and Fe4S4… | x-ray diffraction | A | SF4, MAE, CL, NH4 | — |
| 5KTR | Crystal structure of pyrococcus horikoshii quinolinate synthase (nada) with bound maleate and FE4S4… | x-ray diffraction | A | SF4, MAE, CL, NH4 | — |
| 5KTS | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound citraconate and… | x-ray diffraction | A | SF4, CIZ, CL, NH4 | — |
| 5KTS | Crystal structure of pyrococcus horikoshii quinolinate synthase (nada) with bound citraconate and… | x-ray diffraction | A | SF4, CIZ, CL, NH4 | — |
| 5KTT | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound L-malate and… | x-ray diffraction | A | SF4, LMR | — |
| 5KTT | Crystal structure of pyrococcus horikoshii quinolinate synthase (nada) with bound L-malate and… | x-ray diffraction | A | SF4, LMR | — |
| 6NSO | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | x-ray diffraction | A | 13P, SF4 | — |
| 6NSO | An unexpected intermediate in the reaction catalyzed by quinolinate synthase | x-ray diffraction | A | 13P, SF4 | — |
| 6NSU | Crystallographic capture of quinolinate synthase (nada) from pyrococcus horikoshii in its… | x-ray diffraction | A | SF4 | — |
| 6OR8 | An unexpected intermediate in the reaction catalyzed by quinolinate synthase | x-ray diffraction | A | SF4, 5XR, PO4 | — |
| 6ORA | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | x-ray diffraction | A, B | SF4, 5XW, CL, 5XR | 4 (best 0.77) |
| 6ORA | An unexpected intermediate in the reaction catalyzed by quinolinate synthase | x-ray diffraction | A, B | SF4, 5XW, CL, 5XR | — |
| O57767 | AlphaFold monomer V2.0 prediction for quinolinate synthase a (O57767) | — | — | — |
Ligands
- SF4 · Iron/sulfur cluster · in 20 records
- CL · Chloride ion · in 14 records
- NH4 · Ammonium ion · in 8 records
- 13P · 1,3-dihydroxyacetonephosphate · in 4 records
- 5XR · 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid · in 3 records
- 5XW · (2~{Z})-2-(1-oxidanyl-3-oxidanylidene-propyl) iminobutanedioic acid · in 2 records
- CIZ · (~{Z})-2-methylbut-2-enedioic acid · in 2 records
- ITN · 2-methylidenebutanedioic acid · in 2 records
- LMR · (2S)-2-hydroxybutanedioic acid · in 2 records
- MAE · Maleic acid · in 2 records
- NTM · Quinolinic acid · in 2 records
- PO4 · Phosphate ion · in 1 record
Elsewhere
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