UniProt O46427
Cathepsin H (O46427)
Cathepsin H (UniProt O46427), EC 3.4.22.16: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O46427
- Protein
- Cathepsin H
- EC
- 3.4.22.16
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
Structures
7 records of O46427 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NB3 | Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can… | x-ray diffraction | A, P, B, R, C, S, D, T | — | — |
| 1NB3 | Crystal structure of stefin a in complex with cathepsin H: N-terminal residues of inhibitors can… | x-ray diffraction | A, P, B, R, C, S, D, T | — | — |
| 1NB5 | Crystal structure of stefin A in complex with cathepsin H | x-ray diffraction | A, P, B, R, C, S, D, T | — | — |
| 1NB5 | Crystal structure of stefin a in complex with cathepsin H | x-ray diffraction | A, P, B, R, C, S, D, T | — | — |
| 8PCH | Crystal structure of porcine cathepsin H determined at 2.1 ångström resolution: location of the… | x-ray diffraction | A | NAG, BMA | — |
| 8PCH | Crystal structure of porcine cathepsin H determined at 2.1 ångström resolution: location of the… | x-ray diffraction | A | NAG, BMA | — |
| O46427 | AlphaFold monomer V2.0 prediction for pro-cathepsin H (O46427) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1NB3 chain B against the predicted model O46427: TM-score 0.99, RMSD 0.43 Å
- 1NB3 chain B against the predicted model O46427: TM-score 0.99, RMSD 0.43 Å
- 8PCH chain A against the predicted model O46427: TM-score 0.99, RMSD 0.43 Å
- 8PCH chain A against the predicted model O46427: TM-score 0.99, RMSD 0.43 Å
- 1NB5 chain A against the predicted model O46427: TM-score 0.99, RMSD 0.44 Å
- 1NB5 chain A against the predicted model O46427: TM-score 0.99, RMSD 0.44 Å
- 1NB3 chain C against the predicted model O46427: TM-score 0.99, RMSD 0.44 Å
- 1NB3 chain C against the predicted model O46427: TM-score 0.99, RMSD 0.44 Å
- 1NB5 chain C against the predicted model O46427: TM-score 0.99, RMSD 0.44 Å
- 1NB5 chain C against the predicted model O46427: TM-score 0.99, RMSD 0.44 Å
Elsewhere
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