UniProt O45730
Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1 (O45730)
Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1 (UniProt O45730), EC 3.1.2.-, 7.6.2.-: 4 experimental structures on GenesisL1, 5 ligands bound, 14 pockets. Binding sites, pockets, druggability and…
- UniProt
- O45730
- Protein
- Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1
- EC
- 3.1.2.-, 7.6.2.-
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 14 · 1 record with a druggable one
Structures
4 records of O45730 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7VWC | Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1 | electron microscopy | A, B | 82T | — |
| 7VX8 | Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1 | electron microscopy | B, A | ATP, MG | 14 (best 0.87) |
| 7VX8 | Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1 | electron microscopy | B, A | ATP, MG | — |
| 7VZB | Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1 | electron microscopy | A, B | Y01, FFI | — |
Ligands
- ATP · Adenosine-5'-triphosphate · in 2 records
- MG · Magnesium ion · in 2 records
- 82T · [(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate · in 1 record
- FFI · S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
Experiment against prediction
- 7VX8 chain B against the predicted model P33897: TM-score 0.92, RMSD 2.87 Å
- 7VX8 chain B against the predicted model P33897: TM-score 0.92, RMSD 2.87 Å
- 7VX8 chain A against the predicted model P33897: TM-score 0.92, RMSD 2.87 Å
- 7VX8 chain A against the predicted model P33897: TM-score 0.92, RMSD 2.87 Å
- 7VZB chain B against the predicted model P33897: TM-score 0.91, RMSD 2.75 Å
- 7VZB chain A against the predicted model P33897: TM-score 0.91, RMSD 2.75 Å
- 7VWC chain B against the predicted model P33897: TM-score 0.80, RMSD 3.27 Å
- 7VWC chain A against the predicted model P33897: TM-score 0.80, RMSD 3.47 Å
Elsewhere
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