UniProt O43909
Exostosin-like 3 (O43909)
Exostosin-like 3 (UniProt O43909), EC 2.4.1.223: 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 72 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43909
- Protein
- Exostosin-like 3
- EC
- 2.4.1.223
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 72 · 4 records with a druggable one
Structures
7 records of O43909 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7AU2 | Cryo-EM structure of human exostosin-like 3 (EXTL3) | electron microscopy | A, B | NAG, BMA, MAN | 20 (best 0.86) |
| 7AU2 | Cryo-EM structure of human exostosin-like 3 (EXTL3) | electron microscopy | A, B | NAG, BMA, MAN | — |
| 7AUA | Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP | electron microscopy | A, B | NAG, BMA, MAN, MN, UDP | 20 (best 0.81) |
| 7AUA | Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with udp | electron microscopy | A, B | NAG, BMA, MAN, MN, UDP | — |
| 8OG1 | Exostosin-like 3 apo enzyme | x-ray diffraction | A | NAG, BMA, MAN | 12 (best 0.73) |
| 8OG4 | Exostosin-like 3 UDP complex | x-ray diffraction | A, B | NAG, BMA, MAN, MN, UDP | 20 (best 0.86) |
| O43909 | AlphaFold monomer V2.0 prediction for exostosin-like 3 (O43909) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7AU2 chain A against the predicted model O43909: TM-score 0.99, RMSD 0.90 Å
- 7AU2 chain B against the predicted model O43909: TM-score 0.99, RMSD 0.90 Å
- 7AU2 chain A against the predicted model O43909: TM-score 0.99, RMSD 0.90 Å
- 7AU2 chain B against the predicted model O43909: TM-score 0.99, RMSD 0.90 Å
- 7AUA chain B against the predicted model O43909: TM-score 0.99, RMSD 0.95 Å
- 7AUA chain B against the predicted model O43909: TM-score 0.99, RMSD 0.95 Å
- 7AUA chain A against the predicted model O43909: TM-score 0.99, RMSD 0.95 Å
- 7AUA chain A against the predicted model O43909: TM-score 0.99, RMSD 0.95 Å
- 8OG4 chain B against the predicted model O43909: TM-score 0.98, RMSD 1.43 Å
- 8OG4 chain A against the predicted model O43909: TM-score 0.98, RMSD 1.44 Å
Elsewhere
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