UniProt O43715
TP53-regulated inhibitor of apoptosis 1 (O43715)
TP53-regulated inhibitor of apoptosis 1 (UniProt O43715): 11 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43715
- Protein
- TP53-regulated inhibitor of apoptosis 1
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 8 · 1 record with a druggable one
Structures
12 records of O43715 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XZS | Crystal Structure of TRIAP1-MBP fusion | x-ray diffraction | A, B | — | — |
| 4XZS | Crystal structure of TRIAP1-mbp fusion | x-ray diffraction | A, B | — | — |
| 4XZV | Crystal Structure of SLMO1-TRIAP1 Complex | x-ray diffraction | A, C, E, G | — | — |
| 4XZV | Crystal structure of SLMO1-TRIAP1 complex | x-ray diffraction | A, C, E, G | — | — |
| 6I3V | x-ray structure of the human mitochondrial PRELID1 in complex with TRIAP1 | x-ray diffraction | A, C | CL | 1 (best 0.49) |
| 6I3V | X-ray structure of the human mitochondrial PRELID1 in complex with TRIAP1 | x-ray diffraction | A, C | CL | — |
| 6I3Y | Crystal structure of the human mitochondrial PRELID1K58V-TRIAP1 complex with PS | x-ray diffraction | A, H | — | — |
| 6I3Y | Crystal structure of the human mitochondrial PRELID1K58V-TRIAP1 complex with ps | x-ray diffraction | A, H | — | — |
| 6I4Y | X-ray structure of the human mitochondrial PRELID3b-TRIAP1 complex | x-ray diffraction | A | GLC | — |
| 6I4Y | X-ray structure of the human mitochondrial PRELID3B-TRIAP1 complex | x-ray diffraction | A | GLC | — |
| 8AG0 | Crystal structure of mutant PRELID3a-TRIAP1 complex - R53E | x-ray diffraction | B | BGC, GLC | 7 (best 0.85) |
| O43715 | AlphaFold monomer V2.0 prediction for TP53-regulated inhibitor of apoptosis 1 (O43715) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6I3V chain A against the predicted model O43715: TM-score 0.96, RMSD 0.37 Å
- 6I3V chain A against the predicted model O43715: TM-score 0.96, RMSD 0.37 Å
- 6I3V chain C against the predicted model O43715: TM-score 0.95, RMSD 0.52 Å
- 8AG0 chain B against the predicted model P0AEX9: TM-score 0.87, RMSD 0.66 Å
- 6I3Y chain H against the predicted model O43715: TM-score 0.90, RMSD 0.95 Å
- 6I3Y chain H against the predicted model O43715: TM-score 0.90, RMSD 0.95 Å
- 6I3Y chain A against the predicted model O43715: TM-score 0.85, RMSD 1.93 Å
- 6I3Y chain A against the predicted model O43715: TM-score 0.85, RMSD 1.93 Å
- 6I4Y chain A against the predicted model O43715: TM-score 0.14, RMSD 1.18 Å
- 6I4Y chain A against the predicted model O43715: TM-score 0.14, RMSD 1.18 Å
Elsewhere
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