UniProt O43447
Peptidyl-prolyl cis-trans isomerase H (O43447)
Peptidyl-prolyl cis-trans isomerase H (UniProt O43447), EC 5.2.1.8: 14 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43447
- Protein
- Peptidyl-prolyl cis-trans isomerase H
- EC
- 5.2.1.8
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 14 · 9 records with a druggable one
Structures
15 records of O43447 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1MZW | Crystal structure of a U4/U6 snRNP complex between human spliceosomal cyclophilin H and a U4/U6-60K… | x-ray diffraction | A | — | 1 (best 0.33) |
| 1MZW | Crystal structure of a U4/U6 snrnp complex between human spliceosomal cyclophilin H and a U4/U6-60K… | x-ray diffraction | A | — | 1 (best 0.33) |
| 1QOI | U4/U6 snRNP-specific cyclophilin SnuCyp-20 | x-ray diffraction | A | — | 1 (best 0.32) |
| 1QOI | U4/U6 snrnp-specific cyclophilin snucyp-20 | x-ray diffraction | A | — | 1 (best 0.32) |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | M | — | 1 (best 0.82) |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | M | — | — |
| 6AHD | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | electron microscopy | W | — | 1 (best 0.82) |
| 8H6K | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | electron microscopy | 4H | — | 1 (best 0.81) |
| 8H6L | Cryo-EM structure of human exon-defined spliceosome in the early B state. | electron microscopy | 4H | — | 1 (best 0.81) |
| 8QO9 | Cryo-EM structure of a human spliceosomal B complex protomer | electron microscopy | W | — | 1 (best 0.83) |
| 8QZS | Cryo-EM structure of the cross-exon B-like complex | electron microscopy | W | — | 1 (best 0.83) |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | W | — | 1 (best 0.83) |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | W | — | 1 (best 0.83) |
| 8RM5 | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | electron microscopy | W | — | 1 (best 0.84) |
| O43447 | AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase H (O43447) | predicted | A | — | 1 (best 0.31) |
Experiment against prediction
- 1MZW chain A against the predicted model O43447: TM-score 0.98, RMSD 0.74 Å
- 1MZW chain A against the predicted model O43447: TM-score 0.98, RMSD 0.74 Å
- 8QO9 chain W against the predicted model O43447: TM-score 0.98, RMSD 0.84 Å
- 8R09 chain W against the predicted model O43447: TM-score 0.98, RMSD 0.83 Å
- 5O9Z chain M against the predicted model O43447: TM-score 0.97, RMSD 0.89 Å
- 5O9Z chain M against the predicted model O43447: TM-score 0.97, RMSD 0.89 Å
- 6AHD chain W against the predicted model O43447: TM-score 0.97, RMSD 0.89 Å
- 8QZS chain W against the predicted model O43447: TM-score 0.97, RMSD 0.89 Å
- 8R0B chain W against the predicted model O43447: TM-score 0.97, RMSD 0.87 Å
- 8H6K chain 4H against the predicted model O43447: TM-score 0.97, RMSD 0.87 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.