UniProt O43293
Death-associated protein kinase 3 (O43293)
Death-associated protein kinase 3 (UniProt O43293), EC 2.7.11.1: 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O43293
- Protein
- Death-associated protein kinase 3
- EC
- 2.7.11.1
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 1 record with a druggable one
Structures
15 records of O43293 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YRP | Catalytic domain of human ZIP kinase phosphorylated at Thr265 | x-ray diffraction | A, B | — | — |
| 1YRP | Catalytic domain of human zip kinase phosphorylated at THR265 | x-ray diffraction | A, B | — | — |
| 2J90 | Crystal structure of human ZIP kinase in complex with a tetracyclic pyridone inhibitor (Pyridone 6) | x-ray diffraction | A, B | — | — |
| 2J90 | Crystal structure of human zip kinase in complex with a tetracyclic pyridone inhibitor (pyridone 6) | x-ray diffraction | A, B | — | — |
| 3BHY | Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with a… | x-ray diffraction | A | — | — |
| 3BHY | Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with a… | x-ray diffraction | A | — | — |
| 3BQR | Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with an… | x-ray diffraction | A | — | — |
| 3BQR | Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with an… | x-ray diffraction | A | — | — |
| 5A6N | Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with compound 2 | x-ray diffraction | A, B | — | — |
| 5A6N | Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with compound 2 | x-ray diffraction | A, B | — | — |
| 5A6O | Crystal structure of the apo form of the unphosphorylated human death associated protein kinase 3… | x-ray diffraction | A, B | — | — |
| 5A6O | Crystal structure of the apo form of the unphosphorylated human death associated protein kinase 3… | x-ray diffraction | A, B | — | — |
| 5VJA | Crystal Structure of human zipper-interacting protein kinase (ZIPK, alias DAPK3) in complex with a… | x-ray diffraction | A, B, C, D | DUK, ILE | 12 (best 0.66) |
| 5VJA | Crystal structure of human zipper-interacting protein kinase (zipk, alias DAPK3) in complex with a… | x-ray diffraction | A, B, C, D | DUK | — |
| O43293 | AlphaFold monomer V2.0 prediction for death-associated protein kinase 3 (O43293) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5VJA chain B against the predicted model O43293: TM-score 0.98, RMSD 0.79 Å
- 5VJA chain B against the predicted model O43293: TM-score 0.98, RMSD 0.79 Å
- 5VJA chain A against the predicted model O43293: TM-score 0.98, RMSD 0.79 Å
- 5VJA chain A against the predicted model O43293: TM-score 0.98, RMSD 0.79 Å
- 1YRP chain B against the predicted model O43293: TM-score 0.97, RMSD 1.19 Å
- 1YRP chain B against the predicted model O43293: TM-score 0.97, RMSD 1.19 Å
- 1YRP chain A against the predicted model O43293: TM-score 0.97, RMSD 1.19 Å
- 1YRP chain A against the predicted model O43293: TM-score 0.97, RMSD 1.19 Å
- 5VJA chain D against the predicted model O43293: TM-score 0.97, RMSD 1.29 Å
- 5VJA chain D against the predicted model O43293: TM-score 0.97, RMSD 1.30 Å
Elsewhere
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