UniProt O43290
U4/U6.U5 tri-snRNP-associated protein 1 (O43290)
U4/U6.U5 tri-snRNP-associated protein 1 (UniProt O43290): 28 experimental structures on GenesisL1, 32 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O43290
- Protein
- U4/U6.U5 tri-snRNP-associated protein 1
- Experimental structures
- 28
- Predicted models
- 0
- Pockets
- 32 · 18 records with a druggable one
Structures
28 records of O43290 in the MolNFT archive: 28 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PYU | The conserved ubiquitin-like protein hub1 plays a critical role in splicing in human cells | x-ray diffraction | C, D, H, L, P, T | — | — |
| 4PYU | The conserved ubiquitin-like protein HUB1 plays a critical role in splicing in human cells | x-ray diffraction | C, D, H, L, P, T | — | — |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | P | — | — |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | P | — | — |
| 6AHD | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | electron microscopy | 9 | — | 2 (best 0.77) |
| 6QW6 | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | electron microscopy | S | — | 3 (best 0.83) |
| 6QX9 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | electron microscopy | S | — | 2 (best 0.82) |
| 8H6E | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | electron microscopy | 4S | — | 2 (best 0.81) |
| 8H6J | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | electron microscopy | 4S | — | — |
| 8H6K | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | electron microscopy | 4J | — | — |
| 8H6L | Cryo-EM structure of human exon-defined spliceosome in the early B state. | electron microscopy | 4J | — | 1 (best 0.77) |
| 8Q7N | cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | electron microscopy | S | — | 2 (best 0.89) |
| 8QO9 | Cryo-EM structure of a human spliceosomal B complex protomer | electron microscopy | S | — | — |
| 8QP8 | Cryo-EM Structure of Pre-B Complex (core part) | electron microscopy | S | — | 1 (best 0.62) |
| 8QP9 | Cryo-EM Structure of Pre-B+AMPPNP Complex (core part) | electron microscopy | S | — | 1 (best 0.85) |
| 8QPA | Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) | electron microscopy | S | — | 2 (best 0.81) |
| 8QPB | Cryo-EM Structure of Pre-B+ATP Complex (core part) | electron microscopy | S | — | 1 (best 0.76) |
| 8QPE | Cryo-EM Structure of Pre-B-like Complex (core part) | electron microscopy | S | — | 1 (best 0.78) |
| 8QPK | Cryo-EM Structure of Pre-B+5'ss Complex (core part) | electron microscopy | S | — | 1 (best 0.83) |
| 8QXD | Cryo-EM structure of the cross-exon pre-B complex | electron microscopy | S | — | 2 (best 0.87) |
| 8QZS | Cryo-EM structure of the cross-exon B-like complex | electron microscopy | S | — | 1 (best 0.81) |
| 8R08 | Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | electron microscopy | S | — | 4 (best 0.86) |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | S | — | — |
| 8R0A | Cryo-EM structure of the cross-exon pre-B+5'ss complex | electron microscopy | S | — | — |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | S | — | 2 (best 0.83) |
| 8RM5 | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | electron microscopy | S | — | 2 (best 0.85) |
| 8Y6O | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP… | electron microscopy | S | — | 2 (best 0.86) |
| O43290 | AlphaFold monomer V2.0 prediction for U4/U6.U5 tri-snrnp-associated protein 1 (O43290) | — | — | — |
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.